Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetBeta-secretase 1(Homo sapiens (Human))
Wyeth

Curated by ChEMBL
LigandPNGBDBM50315003(CHEMBL1092227 | N-allyl-4-(1-((6-aminopyridin-2-yl...)
Affinity DataIC50:  590nMAssay Description:Inhibition of human recombinant BACE1 expressed CHO cells by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
Wyeth

Curated by ChEMBL
LigandPNGBDBM50315003(CHEMBL1092227 | N-allyl-4-(1-((6-aminopyridin-2-yl...)
Affinity DataIC50:  4.36E+4nMAssay Description:Inhibition of cathepsin D by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Wyeth

Curated by ChEMBL
LigandPNGBDBM50315003(CHEMBL1092227 | N-allyl-4-(1-((6-aminopyridin-2-yl...)
Affinity DataEC50:  4.80E+3nMAssay Description:Inhibition of human recombinant APP in CHO cells assessed as decrease in beta amyloid protein level by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed