Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetCoagulation factor VII(Homo sapiens (Human))
Pfizer

Curated by ChEMBL

LigandBDBM50215422(CHEMBL243107 | N-(4-(4,5-dihydro-1H-imidazol-2-yl)...)Copy SMILESCopy InChI

Affinity DataIC50:  1.25E+4nMAssay Description:Inhibition of factor 7aMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetProthrombin(Homo sapiens (Human))
Pfizer

Curated by ChEMBL

LigandBDBM50215422(CHEMBL243107 | N-(4-(4,5-dihydro-1H-imidazol-2-yl)...)Copy SMILESCopy InChI

Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of factor 2aMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetCoagulation factor X(Homo sapiens (Human))
Pfizer

Curated by ChEMBL

LigandBDBM50215422(CHEMBL243107 | N-(4-(4,5-dihydro-1H-imidazol-2-yl)...)Copy SMILESCopy InChI

Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of factor 10aMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI