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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
4
hits in this display
Target
Arachidonate 5-lipoxygenase-activating protein
(Homo sapiens (Human))
Janssen Pharmaceutica
US Patent
Ligand
BDBM167032
(US9073876, 118 | US9732093, Compound 118)
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Affinity Data
Ki: 10.5nM
Assay Description:
The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
US Patent
Copy BDB DOI
Target
Flap endonuclease 1
(Homo sapiens (Human))
Janssen Pharmaceutica
US Patent
Ligand
BDBM167032
(US9073876, 118 | US9732093, Compound 118)
Copy SMILES
Copy InChI
Affinity Data
Ki: 10.5nM
Assay Description:
The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
US Patent
Copy BDB DOI
Target
Flap endonuclease 1
(Homo sapiens (Human))
Janssen Pharmaceutica
US Patent
Ligand
BDBM167032
(US9073876, 118 | US9732093, Compound 118)
Copy SMILES
Copy InChI
Affinity Data
Ki: 10.5nM
Assay Description:
The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
US Patent
Copy BDB DOI
Target
Arachidonate 5-lipoxygenase-activating protein
(Homo sapiens (Human))
Janssen Pharmaceutica
US Patent
Ligand
BDBM167032
(US9073876, 118 | US9732093, Compound 118)
Copy SMILES
Copy InChI
Affinity Data
IC50: 66nM
Assay Description:
Inhibition of FLAP in human whole blood assessed as reduction in LTB4 level preincubated for 15 mins followed by calcium ionophore A23187 addition an...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
PubMed
Copy BDB DOI