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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 9 hits in this display   

TargetAdenosine receptor A2a(Homo sapiens (Human))
Shanghaitech University

Curated by ChEMBL
LigandPNGBDBM50604925(CHEMBL5199428)
Affinity DataKi:  164nMAssay Description:Displacement of [3H]SCH5826 from human A2AAR incubated for 60 mins by scintillation counter analysisMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
Shanghaitech University

Curated by ChEMBL
LigandPNGBDBM50604925(CHEMBL5199428)
Affinity DataKi:  503nMAssay Description:Displacement of [3H]DPCPX from human A1AR incubated for 60 mins by scintillation counter analysisMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Shanghaitech University

Curated by ChEMBL
LigandPNGBDBM50604925(CHEMBL5199428)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]HEMADO from human A3AR incubated for 60 mins by scintillation counter analysisMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAdenosine receptor A2b(Homo sapiens (Human))
Shanghaitech University

Curated by ChEMBL
LigandPNGBDBM50604925(CHEMBL5199428)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]DPCPX from human A2BAR incubated for 60 mins by scintillation counter analysisMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Shanghaitech University

Curated by ChEMBL
LigandPNGBDBM50604925(CHEMBL5199428)
Affinity DataIC50:  145nMAssay Description:Inhibition of HDAC1 (unknown origin) using trypsin and LGK(Ac)-AMC as substrates incubated for 1 hr and measured by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
Shanghaitech University

Curated by ChEMBL
LigandPNGBDBM50604925(CHEMBL5199428)
Affinity DataIC50:  240nMAssay Description:Inhibition of HDAC2 (unknown origin) using trypsin and LGK(Ac)-AMC as substrates incubated for 1 hr and measured by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
Shanghaitech University

Curated by ChEMBL
LigandPNGBDBM50604925(CHEMBL5199428)
Affinity DataIC50:  444nMAssay Description:Inhibition of HDAC3 (unknown origin) using trypsin and LGK(Ac)-AMC as substrates incubated for 1 hr and measured by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Shanghaitech University

Curated by ChEMBL
LigandPNGBDBM50604925(CHEMBL5199428)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of HDAC8 (unknown origin) using trypsin and LGK(Ac)-AMC as substrates incubated for 1 hr and measured by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Shanghaitech University

Curated by ChEMBL
LigandPNGBDBM50604925(CHEMBL5199428)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of HDAC6 (unknown origin) using trypsin and LGK(Ac)-AMC as substrates incubated for 1 hr and measured by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails PubMed