Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 6 hits in this display   

TargetHistamine H4 receptor(Rattus norvegicus (rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM26400(2,4-diamino-5,6-disubstituted pyrimidine, 14 | 9-p...)
Affinity DataKi:  4.47nMAssay Description:Displacement of [3H]-histamine from rat histamine H4 receptor after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H4 receptor(Rattus norvegicus (rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM26400(2,4-diamino-5,6-disubstituted pyrimidine, 14 | 9-p...)
Affinity DataKi:  4.5nM ΔG°:  -47.6kJ/molepH: 7.4 T: 2°CAssay Description:Competition radioligand binding assays were performed with increasing concentrations of test compound in the presence of [3H]ligand. All binding reac...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H4 receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM26400(2,4-diamino-5,6-disubstituted pyrimidine, 14 | 9-p...)
Affinity DataKi:  39.8nMAssay Description:Displacement of [3H]-histamine from human histamine H4 receptor expressed in HEK293 cells after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H4 receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM26400(2,4-diamino-5,6-disubstituted pyrimidine, 14 | 9-p...)
Affinity DataKi:  40nM ΔG°:  -42.2kJ/molepH: 7.4 T: 2°CAssay Description:Competition radioligand binding assays were performed with increasing concentrations of test compound in the presence of [3H]ligand. All binding reac...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM26400(2,4-diamino-5,6-disubstituted pyrimidine, 14 | 9-p...)
Affinity DataKi:  661nMAssay Description:Displacement of [3H]NAMH from rat histamine H3 receptor expressed in C6 cells after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM26400(2,4-diamino-5,6-disubstituted pyrimidine, 14 | 9-p...)
Affinity DataKi:  2.24E+3nMAssay Description:Displacement of [3H]NAMH from human histamine H3 receptor expressed in C6 cells after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed