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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
28
hits in this display
Target
5'-nucleotidase
(Rattus norvegicus (Rat))
University Of Bonn
Curated by
ChEMBL
Ligand
BDBM50368125
(ADENOSINE DIPHOSPHATE | ADP)
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Affinity Data
Ki: 0.910nM
Assay Description:
Inhibition of rat ecto-5'-nucleotidase expressed in Sf9 cells by capillary electrophoresis method
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Target
Phosphatidylinositol 4-kinase type 2-alpha
(Homo sapiens (Human))
Smith Kline & French Research
Curated by
ChEMBL
Ligand
BDBM50368125
(ADENOSINE DIPHOSPHATE | ADP)
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Affinity Data
Ki: 1.00E+5nM
Assay Description:
Binding affinity (Ki) against human phosphatidylinositol 4-kinase
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Target
2-dehydropantoate 2-reductase
(Escherichia coli (strain K12))
University Chemical Laboratory
Curated by
ChEMBL
Ligand
BDBM50368125
(ADENOSINE DIPHOSPHATE | ADP)
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Affinity Data
Ki: 1.05E+6nM
Assay Description:
Inhibition of Escherichia coli KPR
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Target
Sensor protein kinase WalK
(Staphylococcus aureus)
Indiana University
Curated by
ChEMBL
Ligand
BDBM50368125
(ADENOSINE DIPHOSPHATE | ADP)
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Affinity Data
IC50: 7.19E+3nM
Assay Description:
Inhibition of Streptococcus pneumoniae VicK autophosphorylation using compound at non-aggregating concentration after 30 mins in presence of [gamma-3...
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Target
Endoplasmin
(Canis familiaris)
Memorial Sloan-Kettering Cancer Center
Curated by
ChEMBL
Ligand
BDBM50368125
(ADENOSINE DIPHOSPHATE | ADP)
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Affinity Data
IC50: 1.14E+4nM
Assay Description:
Displacement of 5-(3-(3-(6-amino-8-(6-iodobenzo[d][1,3]dioxol-5-ylthio)-9H-purin-9-yl)propyl)thioureido)-2-(6-hydroxy-3-oxo-3H-xanthen-9-yl)benzoic a...
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Target
Heat shock protein 75 kDa, mitochondrial
(Homo sapiens (Human))
Memorial Sloan-Kettering Cancer Center
Curated by
ChEMBL
Ligand
BDBM50368125
(ADENOSINE DIPHOSPHATE | ADP)
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Affinity Data
IC50: 5.56E+4nM
Assay Description:
Displacement of 5-(3-(3-(6-amino-8-(6-iodobenzo[d][1,3]dioxol-5-ylthio)-9H-purin-9-yl)propyl)thioureido)-2-(6-hydroxy-3-oxo-3H-xanthen-9-yl)benzoic a...
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Target
Phosphatidylinositol 4-kinase type 2-alpha
(Homo sapiens (Human))
Smith Kline & French Research
Curated by
ChEMBL
Ligand
BDBM50368125
(ADENOSINE DIPHOSPHATE | ADP)
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Affinity Data
IC50: 1.45E+5nM
Assay Description:
Inhibitory activity (IC50) against human phosphatidylinositol 4-kinase at the ATP binding site
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Target
P2X purinoceptor 3
(Homo sapiens (Human))
National Institute Of Diabetes
Curated by
ChEMBL
Ligand
BDBM50368125
(ADENOSINE DIPHOSPHATE | ADP)
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Affinity Data
EC50: >1.00E+5nM
Assay Description:
The compound was evaluated for antagonist activity against recombinant rat P2X purinoceptor 3 (P2X3) at 10 uM, expressed in Xenopus oocytes
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Target
P2X purinoceptor 4
(RAT)
National Institute Of Diabetes
Curated by
ChEMBL
Ligand
BDBM50368125
(ADENOSINE DIPHOSPHATE | ADP)
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Affinity Data
EC50: 2.80E+4nM
Assay Description:
The compound was evaluated for antagonist activity against recombinant rat P2X purinoceptor 4 (P2X4) 3 uM
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Target
P2X purinoceptor 1
(Homo sapiens (Human))
National Institute Of Diabetes
Curated by
ChEMBL
Ligand
BDBM50368125
(ADENOSINE DIPHOSPHATE | ADP)
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Affinity Data
EC50: 1.00E+4nM
Assay Description:
The compound was evaluated for antagonist activity against recombinant human P2X purinoceptor 1 (P2X1 )
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Target
P2X purinoceptor 5
(Rattus norvegicus)
National Institute Of Diabetes
Curated by
ChEMBL
Ligand
BDBM50368125
(ADENOSINE DIPHOSPHATE | ADP)
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Affinity Data
EC50: 1.80E+4nM
Assay Description:
Antagonist activity against recombinant rat P2X purinoceptor 5 (P2X5)
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Target
P2Y purinoceptor 12
(Rattus norvegicus)
National Institute Of Diabetes
Curated by
ChEMBL
Ligand
BDBM50368125
(ADENOSINE DIPHOSPHATE | ADP)
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Affinity Data
EC50: 69nM
Assay Description:
Antagonist activity against phospholipase C coupled rat P2Y purinoceptor 12 (P2Y12)
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Target
Endoplasmin
(Canis familiaris)
Memorial Sloan-Kettering Cancer Center
Curated by
ChEMBL
Ligand
BDBM50368125
(ADENOSINE DIPHOSPHATE | ADP)
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Affinity Data
EC50: 2.10E+4nM
Assay Description:
Inhibition of BODIPY-AG binding to dog Grp94
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Target
2-dehydropantoate 2-reductase
(Escherichia coli (strain K12))
University Chemical Laboratory
Curated by
ChEMBL
Ligand
BDBM50368125
(ADENOSINE DIPHOSPHATE | ADP)
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Affinity Data
Kd: 3.60E+5nM
Assay Description:
Binding affinity to Escherichia coli KPR
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Target
P2Y purinoceptor 6
(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by
ChEMBL
Ligand
BDBM50368125
(ADENOSINE DIPHOSPHATE | ADP)
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Affinity Data
EC50: 6.50E+4nM
Assay Description:
Agonist activity at human recombinant P2Y6 receptor expressed in 1321N1 cells assessed as PLC-mediated [3H]IP production
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Target
P2Y purinoceptor 11
(Homo sapiens (Human))
Bar-Ilan University
Curated by
ChEMBL
Ligand
BDBM50368125
(ADENOSINE DIPHOSPHATE | ADP)
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Affinity Data
EC50: 1.70E+3nM
Assay Description:
Agonist activity at human GFP-tagged P2Y11R transfected in human 1321N1 cells assessed as induction of intracellular calcium mobilization by fluoresc...
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P2Y purinoceptor 1
(Homo sapiens (Human))
Bar-Ilan University
Curated by
ChEMBL
Ligand
BDBM50368125
(ADENOSINE DIPHOSPHATE | ADP)
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Affinity Data
EC50: 24nM
Assay Description:
Agonist activity at human GFP-tagged P2Y1R transfected in human 1321N1 cells assessed as induction of intracellular calcium mobilization by fluoresce...
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Target
P2Y purinoceptor 1
(Meleagris gallopavo)
Bar-Ilan University
Curated by
ChEMBL
Ligand
BDBM50368125
(ADENOSINE DIPHOSPHATE | ADP)
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Affinity Data
EC50: 100nM
Assay Description:
Agonist activity at turkey P2Y1 receptor expressed in human 1321N1 cells assessed as increase in intracellular calcium concentration by dual-excitati...
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Target
Mitogen-activated protein kinase kinase kinase 7
(Homo sapiens (Human))
Chugai Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50368125
(ADENOSINE DIPHOSPHATE | ADP)
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Affinity Data
Kd: 4.10E+3nM
Assay Description:
Binding affinity to recombinant human biotinylated N-terminal GST-tagged autophosphorylated TAK1 (1 to 303 residues) fused with TAB1 (437 to 504 resi...
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Target
Mitogen-activated protein kinase kinase kinase 7
(Homo sapiens (Human))
Chugai Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50368125
(ADENOSINE DIPHOSPHATE | ADP)
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Affinity Data
Kd: 6.30E+4nM
Assay Description:
Binding affinity to recombinant human biotinylated N-terminal GST-tagged non-autophosphorylated TAK1 (1 to 303 residues) fused with TAB1 (437 to 504 ...
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Target
P2X purinoceptor 6
(Rattus norvegicus)
National Institute Of Diabetes
Curated by
ChEMBL
Ligand
BDBM50368125
(ADENOSINE DIPHOSPHATE | ADP)
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Affinity Data
EC50: 1.10E+4nM
Assay Description:
Antagonist activity against recombinant rat P2X purinoceptor 6 (P2X6 )
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Target
P2X purinoceptor 2
(Homo sapiens (Human))
National Institute Of Diabetes
Curated by
ChEMBL
Ligand
BDBM50368125
(ADENOSINE DIPHOSPHATE | ADP)
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Affinity Data
EC50: >1.00E+5nM
Assay Description:
The compound was evaluated for antagonist activity against recombinant human receptor P2X purinoceptor 2 (P2X2 )
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Target
P2Y purinoceptor 2
(Homo sapiens (Human))
National Institute Of Diabetes
Curated by
ChEMBL
Ligand
BDBM50368125
(ADENOSINE DIPHOSPHATE | ADP)
Copy SMILES
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Affinity Data
EC50: >1.00E+5nM
Assay Description:
Evaluated for agonist activity against phospholipase C coupled recombinant human P2Y purinoceptor 2 (P2Y2)
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Target
Heat shock cognate 71 kDa protein
(Homo sapiens (Human))
The Institute Of Cancer Research
Curated by
ChEMBL
Ligand
BDBM50368125
(ADENOSINE DIPHOSPHATE | ADP)
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Affinity Data
Kd: 320nM
Assay Description:
Binding affinity to human truncated HSC70 NBD (1 to 381 residues) by SPR analysis
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Target
Heat shock cognate 71 kDa protein
(Homo sapiens (Human))
The Institute Of Cancer Research
Curated by
ChEMBL
Ligand
BDBM50368125
(ADENOSINE DIPHOSPHATE | ADP)
Copy SMILES
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Affinity Data
Kd: 324nM
Assay Description:
Binding affinity to human truncated HSC70 NBD (1 to 381 residues) by SPR analysis
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Target
P2Y purinoceptor 1
(Homo sapiens (Human))
Bar-Ilan University
Curated by
ChEMBL
Ligand
BDBM50368125
(ADENOSINE DIPHOSPHATE | ADP)
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Affinity Data
EC50: 24nM
Assay Description:
Agonist activity at GFP-tagged human P2Y1R transfected in human 1321N1 cells assessed as increase in intracellular Ca2+ level by fura 2/AM probe-base...
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Target
P2Y purinoceptor 1
(Meleagris gallopavo)
Bar-Ilan University
Curated by
ChEMBL
Ligand
BDBM50368125
(ADENOSINE DIPHOSPHATE | ADP)
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Affinity Data
EC50: 8.00E+3nM
Assay Description:
Evaluated for agonist activity against phospholipase C coupled P2Y purinoceptor 1 (P2Y1) of turkey erythrocytes
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Target
P2Y purinoceptor 11
(Homo sapiens (Human))
Bar-Ilan University
Curated by
ChEMBL
Ligand
BDBM50368125
(ADENOSINE DIPHOSPHATE | ADP)
Copy SMILES
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Affinity Data
EC50: 1.70E+3nM
Assay Description:
Agonist activity at GFP-tagged human P2Y11R transfected in human 1321N1 cells assessed as increase in intracellular Ca2+ level by fura 2/AM probe-bas...
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