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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 17 hits in this display   

TargetHistone deacetylase 1(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50437405(CHEMBL2408778)
Affinity DataKi:  0.260nMAssay Description:Inhibition of HDAC1 (unknown origin) by Fluor de Lys based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50437405(CHEMBL2408778)
Affinity DataKi:  0.260nMAssay Description:Inhibition of human recombinant HDAC1 using Ac-Leu-Gly-Lys(Ac)AMCA as substrate after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50437405(CHEMBL2408778)
Affinity DataKi:  138nMAssay Description:Inhibition of c-Src (unknown origin) after 10 mins by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50437405(CHEMBL2408778)
Affinity DataKi:  138nMAssay Description:Inhibition of c-Src (unknown origin) by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase HCK(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50437405(CHEMBL2408778)
Affinity DataKi:  504nMAssay Description:Inhibition of HCK (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50437405(CHEMBL2408778)
Affinity DataKi:  2.35E+3nMAssay Description:Inhibition of c-Abl (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50437405(CHEMBL2408778)
Affinity DataIC50:  2.70nMAssay Description:Inhibition of HDAC6 (unknown origin) using fluorogenic peptide from p53 residues (379 to 382) (RHKK(Ac)) as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50437405(CHEMBL2408778)
Affinity DataIC50:  19nMAssay Description:Inhibition of HDAC3 (unknown origin) using fluorogenic peptide from p53 residues (379 to 382) (RHKK(Ac)) as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50437405(CHEMBL2408778)
Affinity DataIC50:  51nMAssay Description:Inhibition of HDAC10 (unknown origin) using fluorogenic peptide from p53 residues (379 to 382) (RHKK(Ac)) as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50437405(CHEMBL2408778)
Affinity DataIC50:  86nMAssay Description:Inhibition of HDAC1 (unknown origin) using fluorogenic peptide from p53 residues (379 to 382) (RHKK(Ac)) as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 11(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50437405(CHEMBL2408778)
Affinity DataIC50:  224nMAssay Description:Inhibition of HDAC11 (unknown origin) using fluorogenic peptide from p53 residues (379 to 382) (RHKK(Ac)) as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50437405(CHEMBL2408778)
Affinity DataIC50:  231nMAssay Description:Inhibition of HDAC2 (unknown origin) using fluorogenic peptide from p53 residues (379 to 382) (RHKK(Ac)) as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50437405(CHEMBL2408778)
Affinity DataIC50:  2.31E+3nMAssay Description:Inhibition of HDAC8 (unknown origin) using fluorogenic peptide from p53 residues (379 to 382) (RHK(Ac)K(Ac)) as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 5(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50437405(CHEMBL2408778)
Affinity DataIC50:  3.89E+3nMAssay Description:Inhibition of HDAC5 (unknown origin) using Boc-Lys(trifluoroacetyl)-AMC as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50437405(CHEMBL2408778)
Affinity DataIC50:  3.98E+3nMAssay Description:Inhibition of HDAC4 (unknown origin) using Boc-Lys(trifluoroacetyl)-AMC as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 7(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50437405(CHEMBL2408778)
Affinity DataIC50:  1.32E+4nMAssay Description:Inhibition of HDAC7 (unknown origin) using Boc-Lys(trifluoroacetyl)-AMC as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 9(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50437405(CHEMBL2408778)
Affinity DataIC50:  2.80E+4nMAssay Description:Inhibition of HDAC9 (unknown origin) using Boc-Lys(trifluoroacetyl)-AMC as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed