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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
15
hits in this display
Target
Cytochrome P450 1A2
(Homo sapiens (Human))
De Montfort University
Curated by
ChEMBL
Ligand
BDBM42528
((E)-3-(1-naphthalenyl)-1-pyridin-4-yl-2-propen-1-o...)
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Affinity Data
IC50: 28nM
Assay Description:
Inhibition of recombinant human CYP1A2 expressed in HEK293 cells using 3-cyano-7-ethoxycoumarin as substrate pretreated for 30 mins followed by subst...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
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PC cid
PC sid
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In Depth
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Article
PubMed
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Target
Cytochrome P450 1A2
(Homo sapiens (Human))
De Montfort University
Curated by
ChEMBL
Ligand
BDBM42528
((E)-3-(1-naphthalenyl)-1-pyridin-4-yl-2-propen-1-o...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 35nM
Assay Description:
Inhibition of human CYP1A2 expressed in yeast microsomal membranes using 3-cyano-7-ethoxycoumarin as substrate measured after 10 mins by fluorescence...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
Patents
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cytochrome P450 1A1
(Homo sapiens (Human))
De Montfort University
Curated by
ChEMBL
Ligand
BDBM42528
((E)-3-(1-naphthalenyl)-1-pyridin-4-yl-2-propen-1-o...)
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Copy InChI
Affinity Data
IC50: 510nM
Assay Description:
Inhibition of human CYP1A1 expressed in yeast microsomal membranes using 7-ethoxyresorufin as substrate measured after 10 mins by fluorescence assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
Patents
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cytochrome P450 1A1
(Homo sapiens (Human))
De Montfort University
Curated by
ChEMBL
Ligand
BDBM42528
((E)-3-(1-naphthalenyl)-1-pyridin-4-yl-2-propen-1-o...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 550nM
Assay Description:
Inhibition of recombinant human CYP1A1 expressed in HEK293 cells using 7-ethoxyresorufin as substrate pretreated for 30 mins followed by substrate ad...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
Patents
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cytochrome P450 1B1
(Homo sapiens (Human))
De Montfort University
Curated by
ChEMBL
Ligand
BDBM42528
((E)-3-(1-naphthalenyl)-1-pyridin-4-yl-2-propen-1-o...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 650nM
Assay Description:
Inhibition of human CYP1B1 expressed in yeast microsomal membranes using 7-ethoxyresorufin as substrate measured after 10 mins by fluorescence assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
Patents
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cytochrome P450 1B1
(Homo sapiens (Human))
De Montfort University
Curated by
ChEMBL
Ligand
BDBM42528
((E)-3-(1-naphthalenyl)-1-pyridin-4-yl-2-propen-1-o...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 750nM
Assay Description:
Inhibition of recombinant human CYP1B1 expressed in HEK293 cells using 7-ethoxyresorufin as substrate pretreated for 30 mins followed by substrate ad...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
Patents
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Neuropeptide Y receptor type 1
(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center
Curated by
PubChem BioAssay
Ligand
BDBM42528
((E)-3-(1-naphthalenyl)-1-pyridin-4-yl-2-propen-1-o...)
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Affinity Data
IC50: 5.47E+3nM
Assay Description:
Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: The Scripps Research Institute, TSRI Assay Provide...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
Patents
In Depth
Details
PCBioAssay
Copy BDB DOI
Target
Cytochrome P450 2D6
(Homo sapiens (Human))
De Montfort University
Curated by
ChEMBL
Ligand
BDBM42528
((E)-3-(1-naphthalenyl)-1-pyridin-4-yl-2-propen-1-o...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of recombinant human CYP2D6 expressed in HEK293 cells using 7-ethoxy-methyloxy-3-cyanocoumarin as substrate pretreated for 30 mins followe...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
Patents
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cytochrome P450 2C9
(Homo sapiens (Human))
De Montfort University
Curated by
ChEMBL
Ligand
BDBM42528
((E)-3-(1-naphthalenyl)-1-pyridin-4-yl-2-propen-1-o...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of recombinant human CYP2C9 expressed in HEK293 cells using 3-cyano-7-ethoxycoumarin as substrate pretreated for 30 mins followed by subst...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
Patents
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cytochrome P450 3A4
(Homo sapiens (Human))
De Montfort University
Curated by
ChEMBL
Ligand
BDBM42528
((E)-3-(1-naphthalenyl)-1-pyridin-4-yl-2-propen-1-o...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of recombinant human CYP3A4 expressed in HEK293 cells using dibenzylfluorescein as substrate pretreated for 30 mins followed by substrate ...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
Patents
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cytochrome P450 2C19
(Homo sapiens (Human))
De Montfort University
Curated by
ChEMBL
Ligand
BDBM42528
((E)-3-(1-naphthalenyl)-1-pyridin-4-yl-2-propen-1-o...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of recombinant human CYP2C19 expressed in HEK293 cells using 3-cyano-7-ethoxycoumarin as substrate pretreated for 30 mins followed by subs...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
Patents
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cytochrome P450 2D6
(Homo sapiens (Human))
De Montfort University
Curated by
ChEMBL
Ligand
BDBM42528
((E)-3-(1-naphthalenyl)-1-pyridin-4-yl-2-propen-1-o...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.80E+4nM
Assay Description:
Inhibition of human CYP2D6 expressed in yeast microsomal membranes using 7-ethoxy-methyloxy-3-cyanocoumarin as substrate measured after 10 mins by fl...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
Patents
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cytochrome P450 2C9
(Homo sapiens (Human))
De Montfort University
Curated by
ChEMBL
Ligand
BDBM42528
((E)-3-(1-naphthalenyl)-1-pyridin-4-yl-2-propen-1-o...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >2.00E+4nM
Assay Description:
Inhibition of human CYP2C9 expressed in yeast microsomal membranes using 3-cyano-7-ethoxycoumarin as substrate measured after 10 mins by fluorescence...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
Patents
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cytochrome P450 2C19
(Homo sapiens (Human))
De Montfort University
Curated by
ChEMBL
Ligand
BDBM42528
((E)-3-(1-naphthalenyl)-1-pyridin-4-yl-2-propen-1-o...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >2.00E+4nM
Assay Description:
Inhibition of human CYP2C19 expressed in yeast microsomal membranes using 3-cyano-7-ethoxycoumarin as substrate measured after 10 mins by fluorescenc...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
Patents
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cytochrome P450 3A4
(Homo sapiens (Human))
De Montfort University
Curated by
ChEMBL
Ligand
BDBM42528
((E)-3-(1-naphthalenyl)-1-pyridin-4-yl-2-propen-1-o...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >2.00E+4nM
Assay Description:
Inhibition of human CYP3A4 expressed in yeast microsomal membranes using dibenzylfluorescein as substrate measured after 10 mins by fluorescence assa...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
Patents
In Depth
Details
Article
PubMed
Copy BDB DOI