Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 4 hits in this display   

TargetProlyl endopeptidase(Sus scrofa)
TBA

Curated by ChEMBL

LigandBDBM50291163(4-Phenyl-1-{(S)-2-[(R)-2-(thiazole-2-carbonyl)-pyr...)Copy SMILESCopy InChI

Affinity DataIC50:  4.40nMAssay Description:The compound was tested for the inhibitory activity against prolyl endo peptidase(PEP) enzymeMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
DrugBankGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails Article
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TargetProlyl endopeptidase(Sus scrofa)
TBA

Curated by ChEMBL

LigandBDBM50291163(4-Phenyl-1-{(S)-2-[(R)-2-(thiazole-2-carbonyl)-pyr...)Copy SMILESCopy InChI

Affinity DataIC50:  6.02E+3nMAssay Description:In vitro inhibitory activity against prolyl endopeptidase (PEP)More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
DrugBankGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetSerine protease 1(Bos taurus (bovine))
TBA

Curated by ChEMBL

LigandBDBM50291163(4-Phenyl-1-{(S)-2-[(R)-2-(thiazole-2-carbonyl)-pyr...)Copy SMILESCopy InChI

Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of trypsinMore data for this Ligand-Target Pair

Target InfoPDBMMDBKEGG
UniProtKB/SwissProt
B.MOADDrugBankGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails Article
Copy BDB DOI

TargetProthrombin(Homo sapiens (Human))
TBA

Curated by ChEMBL

LigandBDBM50291163(4-Phenyl-1-{(S)-2-[(R)-2-(thiazole-2-carbonyl)-pyr...)Copy SMILESCopy InChI

Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails Article
Copy BDB DOI