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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
14
hits in this display
Target
Prolyl endopeptidase FAP
(Homo sapiens (Human))
National Health Research Institutes
Curated by
ChEMBL
Ligand
BDBM50326374
((S)-N-(2-(2-cyanopyrrolidin-1-yl)-2-oxoethyl)-1-na...)
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Affinity Data
IC50: 610nM
Assay Description:
Inhibition of human recombinant FAP expressed in Hi5 insect cells
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
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Target
Prolyl endopeptidase FAP
(Mus musculus (Mouse))
University Of Antwerp (Ua)
Curated by
ChEMBL
Ligand
BDBM50326374
((S)-N-(2-(2-cyanopyrrolidin-1-yl)-2-oxoethyl)-1-na...)
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Affinity Data
IC50: 670nM
Assay Description:
Inhibition of mouse recombinant FAP expressed in HEK293 cells assessed as pNA release from Ala-Pro-p-nitroanilide pre-incubated with enzyme for 15 mi...
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
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Target
Prolyl endopeptidase FAP
(Mus musculus (Mouse))
University Of Antwerp (Ua)
Curated by
ChEMBL
Ligand
BDBM233320
(US9346814, Ref. Cmpd No 2)
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Affinity Data
IC50: 670nM
pH: 8.3 T: 2°C
Assay Description:
Enzyme activities were determined kinetically in a final volume of 200 μl for 10 minutes at 37° C. by measuring the initial velocities of pNA ...
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Prolyl endopeptidase
(Homo sapiens (Human))
University Of Antwerp (Ua)
Curated by
ChEMBL
Ligand
BDBM50326374
((S)-N-(2-(2-cyanopyrrolidin-1-yl)-2-oxoethyl)-1-na...)
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Affinity Data
IC50: 3.30E+3nM
Assay Description:
Inhibition of human recombinant PREP expressed in Escherichia coli assessed as pNA release from Z-Gly-Pro-p-nitroanilide pre-incubated with enzyme fo...
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Prolyl endopeptidase
(Homo sapiens (Human))
University Of Antwerp (Ua)
Curated by
ChEMBL
Ligand
BDBM233320
(US9346814, Ref. Cmpd No 2)
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Copy InChI
Affinity Data
IC50: 3.60E+3nM
pH: 8.3 T: 2°C
Assay Description:
Enzyme activities were determined kinetically in a final volume of 200 μl for 10 minutes at 37° C. by measuring the initial velocities of pNA ...
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Dipeptidyl peptidase 8
(Homo sapiens (Human))
National Health Research Institutes
Curated by
ChEMBL
Ligand
BDBM50326374
((S)-N-(2-(2-cyanopyrrolidin-1-yl)-2-oxoethyl)-1-na...)
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Affinity Data
IC50: >1.00E+5nM
Assay Description:
Inhibition of human recombinant His-tagged DPP8 expressed in insect cells
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Dipeptidyl peptidase 9
(Homo sapiens (Human))
National Health Research Institutes
Curated by
ChEMBL
Ligand
BDBM50326374
((S)-N-(2-(2-cyanopyrrolidin-1-yl)-2-oxoethyl)-1-na...)
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Affinity Data
IC50: >1.00E+5nM
Assay Description:
Inhibition of human recombinant His-tagged DPP9 expressed in insect cells
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Dipeptidyl peptidase 2
(Homo sapiens (Human))
National Health Research Institutes
Curated by
ChEMBL
Ligand
BDBM50326374
((S)-N-(2-(2-cyanopyrrolidin-1-yl)-2-oxoethyl)-1-na...)
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Affinity Data
IC50: >1.00E+5nM
Assay Description:
Inhibition of human recombinant His-tagged DPP2 expressed in insect cells
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Dipeptidyl peptidase 4
(Homo sapiens (Human))
National Health Research Institutes
Curated by
ChEMBL
Ligand
BDBM50326374
((S)-N-(2-(2-cyanopyrrolidin-1-yl)-2-oxoethyl)-1-na...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+5nM
Assay Description:
Inhibition of human recombinant His-tagged DPP4 expressed in insect cells
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Dipeptidyl peptidase 2
(Homo sapiens (Human))
National Health Research Institutes
Curated by
ChEMBL
Ligand
BDBM50326374
((S)-N-(2-(2-cyanopyrrolidin-1-yl)-2-oxoethyl)-1-na...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+5nM
Assay Description:
Inhibition of human seminal plasma DPP2 assessed as pNA release from Lys-Ala-p-nitroanilide substrate pre-incubated with enzyme for 15 min prior to s...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Dipeptidyl peptidase 2
(Homo sapiens (Human))
National Health Research Institutes
Curated by
ChEMBL
Ligand
BDBM233320
(US9346814, Ref. Cmpd No 2)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+5nM
pH: 8.3 T: 2°C
Assay Description:
Enzyme activities were determined kinetically in a final volume of 200 μl for 10 minutes at 37° C. by measuring the initial velocities of pNA ...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Dipeptidyl peptidase 9
(Homo sapiens (Human))
National Health Research Institutes
Curated by
ChEMBL
Ligand
BDBM233320
(US9346814, Ref. Cmpd No 2)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+5nM
pH: 8.3 T: 2°C
Assay Description:
Enzyme activities were determined kinetically in a final volume of 200 μl for 10 minutes at 37° C. by measuring the initial velocities of pNA ...
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Dipeptidyl peptidase 4
(Homo sapiens (Human))
National Health Research Institutes
Curated by
ChEMBL
Ligand
BDBM233320
(US9346814, Ref. Cmpd No 2)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+5nM
pH: 8.3 T: 2°C
Assay Description:
Enzyme activities were determined kinetically in a final volume of 200 μl for 10 minutes at 37° C. by measuring the initial velocities of pNA ...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Dipeptidyl peptidase 4
(Homo sapiens (Human))
National Health Research Institutes
Curated by
ChEMBL
Ligand
BDBM50326374
((S)-N-(2-(2-cyanopyrrolidin-1-yl)-2-oxoethyl)-1-na...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+5nM
Assay Description:
Inhibition of human seminal plasma DPP4 assessed as pNA release from Gly-Pro-p-nitroanilide substrate pre-incubated with enzyme for 15 min prior to s...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI