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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 4 hits in this display   

TargetCathepsin S(Homo sapiens (Human))
Currently Naeja Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50121039(CHEMBL114410 | [(S)-2-Cyclohexyl-1-((5S,6R)-4,4,7-...)
Affinity DataIC50:  0.700nMAssay Description:In vitro Inhibitory activity of the compound was determined against Cathepsin S cysteine protease by using Cbz-Val-Arg-AMCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Rattus norvegicus)
Currently Naeja Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50121039(CHEMBL114410 | [(S)-2-Cyclohexyl-1-((5S,6R)-4,4,7-...)
Affinity DataIC50:  0.700nMAssay Description:Inhibition of Cbz-Phe-Arg-AMC binding to Cathepsin L cysteine proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Currently Naeja Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50121039(CHEMBL114410 | [(S)-2-Cyclohexyl-1-((5S,6R)-4,4,7-...)
Affinity DataIC50:  7.60nMAssay Description:Inhibition of Cbz-Phe-Arg-AMC binding to Cathepsin K cysteine proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
Currently Naeja Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50121039(CHEMBL114410 | [(S)-2-Cyclohexyl-1-((5S,6R)-4,4,7-...)
Affinity DataIC50:  430nMAssay Description:Inhibitory activity of Cbz-Phe-Arg-AMC against Cathepsin B cysteine proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed