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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 4 hits in this display   

TargetProcathepsin L(Rattus norvegicus)
Currently Naeja Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50121040(CHEMBL117928 | [(S)-2-Pyridin-3-yl-1-((5S,6R)-4,4,...)
Affinity DataIC50:  1.70nMAssay Description:Inhibition of Cbz-Phe-Arg-AMC binding to Cathepsin L cysteine proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Currently Naeja Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50121040(CHEMBL117928 | [(S)-2-Pyridin-3-yl-1-((5S,6R)-4,4,...)
Affinity DataIC50:  2.5nMAssay Description:Inhibition of Cbz-Phe-Arg-AMC binding to Cathepsin K cysteine proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Currently Naeja Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50121040(CHEMBL117928 | [(S)-2-Pyridin-3-yl-1-((5S,6R)-4,4,...)
Affinity DataIC50:  58nMAssay Description:In vitro Inhibitory activity of the compound was determined against Cathepsin S cysteine protease by using Cbz-Val-Arg-AMCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
Currently Naeja Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50121040(CHEMBL117928 | [(S)-2-Pyridin-3-yl-1-((5S,6R)-4,4,...)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibitory activity of Cbz-Phe-Arg-AMC against Cathepsin B cysteine proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed