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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
4
hits in this display
Target
Cathepsin K
(Homo sapiens (Human))
Currently Naeja Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50121038
(CHEMBL113706 | [(S)-2-Thiophen-2-yl-1-((5S,6R)-4,4...)
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Affinity Data
IC50: 1.80nM
Assay Description:
Inhibition of Cbz-Phe-Arg-AMC binding to Cathepsin K cysteine protease
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Procathepsin L
(Rattus norvegicus)
Currently Naeja Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50121038
(CHEMBL113706 | [(S)-2-Thiophen-2-yl-1-((5S,6R)-4,4...)
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Affinity Data
IC50: 3nM
Assay Description:
Inhibition of Cbz-Phe-Arg-AMC binding to Cathepsin L cysteine protease
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cathepsin S
(Homo sapiens (Human))
Currently Naeja Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50121038
(CHEMBL113706 | [(S)-2-Thiophen-2-yl-1-((5S,6R)-4,4...)
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Affinity Data
IC50: 4.60nM
Assay Description:
In vitro Inhibitory activity of the compound was determined against Cathepsin S cysteine protease by using Cbz-Val-Arg-AMC
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cathepsin B
(Homo sapiens (Human))
Currently Naeja Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50121038
(CHEMBL113706 | [(S)-2-Thiophen-2-yl-1-((5S,6R)-4,4...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 430nM
Assay Description:
Inhibitory activity of Cbz-Phe-Arg-AMC against Cathepsin B cysteine protease
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI