Compile Data Set for Download or QSAR
maximum 50k data

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 4 hits in this display   

TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Targacept

Curated by ChEMBL
LigandPNGBDBM50399792(CHEMBL2179862)
Affinity DataKi:  2.80nMAssay Description:Displacement of [3H]epibatidine form human alpha7 nAchR expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
Targacept

Curated by ChEMBL
LigandPNGBDBM50399792(CHEMBL2179862)
Affinity DataKi:  200nMAssay Description:Displacement of [3H]nicotine human alpha4beta2 nAChR in SH-EP1 cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Targacept

Curated by ChEMBL
LigandPNGBDBM50399792(CHEMBL2179862)
Affinity DataKi:  1.86E+4nMAssay Description:Inhibition of human 5HT3RMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Targacept

Curated by ChEMBL
LigandPNGBDBM50399792(CHEMBL2179862)
Affinity DataEC50:  50nMAssay Description:Agonist activity at rat alpha7 nAchR expressed in GH4C1 cells by whole cell patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed