Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)
Found 7 hits in this display
Ataxin-2(Homo sapiens (Human))Hoffmann-La Roche
US Patent
BDBM352374(6-((3aS,6aS)-5-(5-Cyclopropyl-6-(tetrahydro-2H-pyr...)
Ataxin-2(Homo sapiens (Human))Hoffmann-La Roche
US Patent
BDBM352374(6-((3aS,6aS)-5-(5-Cyclopropyl-6-(tetrahydro-2H-pyr...)
Ataxin-1(Homo sapiens (Human))Hoffmann-La Roche
US Patent
BDBM352374(6-((3aS,6aS)-5-(5-Cyclopropyl-6-(tetrahydro-2H-pyr...)
Ataxin-2(Homo sapiens (Human))Hoffmann-La Roche
US Patent
BDBM352374(6-((3aS,6aS)-5-(5-Cyclopropyl-6-(tetrahydro-2H-pyr...)
IC50: 25nMAssay Description:Assay working solutions were made as follows:Assay buffer (50 mM Tris-HCl, 140 mM NaCl, 5 mM KCl, 1 mM CaCl2, 1 mM MgCl2, 0.01% Triton-X-100, pH 8.0;...More data for this Ligand-Target Pair
Ataxin-2(Homo sapiens (Human))Hoffmann-La Roche
US Patent
BDBM352374(6-((3aS,6aS)-5-(5-Cyclopropyl-6-(tetrahydro-2H-pyr...)
IC50: 25nMAssay Description:ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...More data for this Ligand-Target Pair
Ataxin-2(Homo sapiens (Human))Hoffmann-La Roche
US Patent
BDBM352374(6-((3aS,6aS)-5-(5-Cyclopropyl-6-(tetrahydro-2H-pyr...)
IC50: 25nMAssay Description:ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...More data for this Ligand-Target Pair
Ataxin-2(Homo sapiens (Human))Hoffmann-La Roche
US Patent
BDBM352374(6-((3aS,6aS)-5-(5-Cyclopropyl-6-(tetrahydro-2H-pyr...)
IC50: 25nMAssay Description:Assay working solutions were made as follows:Assay buffer (50 mM Tris-HCl, 140 mM NaCl, 5 mM KCl, 1 mM CaCl2, 1 mM MgCl2, 0.01% Triton-X-100, pH 8.0;...More data for this Ligand-Target Pair