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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetNeuronal acetylcholine receptor subunit alpha-4(Homo sapiens (Human))
Targacept

US Patent
LigandPNGBDBM141849(US8921410, Table 1 Compound 10)
Affinity DataKi:  43nM ΔG°:  -41.5kJ/moleT: 2°CAssay Description:The binding of [3H]MLA was measured using a modification of the methods of Davies et al., Neuropharmacol. 38: 679 (1999). [3H]MLA (Specific Activity=...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNeuronal acetylcholine receptor subunit alpha-4(Rattus norvegicus (Rat))
Targacept

US Patent
LigandPNGBDBM141849(US8921410, Table 1 Compound 10)
Affinity DataKi:  230nM ΔG°:  -37.4kJ/moleT: 2°CAssay Description:The binding of [3H]MLA was measured using a modification of the methods of Davies et al., Neuropharmacol. 38: 679 (1999). [3H]MLA (Specific Activity=...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Targacept

US Patent
LigandPNGBDBM141849(US8921410, Table 1 Compound 10)
Affinity DataKi:  3.20E+3nM ΔG°:  -30.9kJ/moleT: 2°CAssay Description:The binding of [3H]MLA was measured using a modification of the methods of Davies et al., Neuropharmacol. 38: 679 (1999). [3H]MLA (Specific Activity=...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent