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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
7
hits in this display
Target
Cathepsin K
(Oryctolagus cuniculus (rabbit))
Celera Genomics
Curated by
ChEMBL
Ligand
BDBM19858
(N-{1-[(cyanomethyl)carbamoyl]cyclohexyl}-4-(morpho...)
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Affinity Data
Ki: 19nM
Assay Description:
Inhibitory constant against rabbit cathepsin K using Z-Phe-Arg-AMC substrate
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
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Target
Cathepsin K
(Oryctolagus cuniculus (rabbit))
Celera Genomics
Curated by
ChEMBL
Ligand
BDBM19858
(N-{1-[(cyanomethyl)carbamoyl]cyclohexyl}-4-(morpho...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 19nM
pH: 5.5 T: 2°C
Assay Description:
Prior to the addition of substrate, different concentrations of the inhibitor ranging from 100 uM to 0.2 nM were preincubated for 15 min with enzyme ...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cathepsin K
(Oryctolagus cuniculus (rabbit))
Celera Genomics
Curated by
ChEMBL
Ligand
BDBM19858
(N-{1-[(cyanomethyl)carbamoyl]cyclohexyl}-4-(morpho...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 72nM EC50: 580nM
pH: 5.5 T: 2°C
Assay Description:
Prior to the addition of substrate, different concentrations of the inhibitor ranging from 100 uM to 0.2 nM were preincubated for 15 min with enzyme ...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cathepsin S
(Mus musculus (Mouse))
Merck Frosst Centre For Therapeutic Research
Ligand
BDBM19858
(N-{1-[(cyanomethyl)carbamoyl]cyclohexyl}-4-(morpho...)
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Copy InChI
Affinity Data
IC50: 4.50E+3nM EC50: 8.50E+3nM
Assay Description:
Prior to the addition of substrate, different concentrations of the inhibitor ranging from 100 uM to 0.2 nM were preincubated for 15 min with enzyme ...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cathepsin B
(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research
Ligand
BDBM19858
(N-{1-[(cyanomethyl)carbamoyl]cyclohexyl}-4-(morpho...)
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Affinity Data
IC50: 1.54E+4nM EC50: 4.40E+3nM
pH: 6.0 T: 2°C
Assay Description:
Prior to the addition of substrate, different concentrations of the inhibitor ranging from 100 uM to 0.2 nM were preincubated for 15 min with enzyme ...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Procathepsin L
(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research
Ligand
BDBM19858
(N-{1-[(cyanomethyl)carbamoyl]cyclohexyl}-4-(morpho...)
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Copy InChI
Affinity Data
IC50: 3.20E+4nM EC50: >1.00E+4nM
pH: 5.5 T: 2°C
Assay Description:
Prior to the addition of substrate, different concentrations of the inhibitor ranging from 100 uM to 0.2 nM were preincubated for 15 min with enzyme ...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cathepsin S
(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research
Ligand
BDBM19858
(N-{1-[(cyanomethyl)carbamoyl]cyclohexyl}-4-(morpho...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 5.20E+4nM EC50: 4.80E+3nM
pH: 6.5 T: 2°C
Assay Description:
Prior to the addition of substrate, different concentrations of the inhibitor ranging from 100 uM to 0.2 nM were preincubated for 15 min with enzyme ...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI