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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
5
hits in this display
Target
Neuronal acetylcholine receptor subunit alpha-7
(Homo sapiens (Human))
Bayer Intellectual Property
US Patent
Ligand
BDBM139026
(US8884017, 51)
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Affinity Data
Ki: 3.90nM ΔG°: -44.6kJ/mole
pH: 7.4 T: 2°C
Assay Description:
The [3H]-methyllycaconitine binding assay is a modification of the method described by Davies et al. in Neuropharmacol. 1999, 38, 679-690.Rat brain t...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
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PC sid
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In Depth
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US Patent
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Target
Neuronal acetylcholine receptor subunit alpha-7
(Homo sapiens (Human))
Bayer Intellectual Property
US Patent
Ligand
BDBM50173952
(Benzo[b]thiophene-2-carboxylic acid (1-aza-bicyclo...)
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Affinity Data
Ki: 14.6nM
Assay Description:
Displacement of [3H]epibatidine form human alpha7 nAchR expressed in HEK293 cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
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In Depth
Details
Article
PubMed
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Target
Neuronal acetylcholine receptor subunit alpha-7
(Homo sapiens (Human))
Bayer Intellectual Property
US Patent
Ligand
BDBM50173952
(Benzo[b]thiophene-2-carboxylic acid (1-aza-bicyclo...)
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Affinity Data
Ki: 14.6nM
Assay Description:
Binding affinity towards human nicotinic acetylcholine receptor alpha 7 expressed in GH4C1 cell using [3H]methyllycaconitine
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
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In Depth
Details
Article
PubMed
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Target
5-hydroxytryptamine receptor 3A
(Homo sapiens (Human))
Targacept
Curated by
ChEMBL
Ligand
BDBM50173952
(Benzo[b]thiophene-2-carboxylic acid (1-aza-bicyclo...)
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Affinity Data
Ki: 49.8nM
Assay Description:
Inhibition of human 5HT3R
More data for this Ligand-Target Pair
Target Info
PDB
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KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
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Article
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Target
5-hydroxytryptamine receptor 3A/3B/3C/3D/3E
(Homo sapiens (Human))
Eli Lilly
Curated by
ChEMBL
Ligand
BDBM50173952
(Benzo[b]thiophene-2-carboxylic acid (1-aza-bicyclo...)
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Affinity Data
Ki: 49.8nM
Assay Description:
Binding affinity for human 5-hydroxytryptamine 3 serotonin membrane receptor using [3H]GR-65630
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI