Home
About
Info
Download
WebServices
Contact
Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
6
hits in this display
Target
Prolyl endopeptidase
(Homo sapiens (Human))
Mcgill University
Curated by
ChEMBL
Ligand
BDBM50312222
(CHEMBL1079579 | N-Benzyloxycarbonylamino-glycine-2...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 20nM
Assay Description:
Inhibition of prolyl oligopeptidase in human LN229 cell extracts assessed as blockade of Z-Gly-Pro-AMC substrate hydrolysis by fluorimetric assay
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Prolyl endopeptidase
(Homo sapiens (Human))
Mcgill University
Curated by
ChEMBL
Ligand
BDBM50312222
(CHEMBL1079579 | N-Benzyloxycarbonylamino-glycine-2...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 20nM
Assay Description:
Inhibition of prolyl oligopeptidase in human LNZ308 cell extracts assessed as blockade of Z-Gly-Pro-AMC substrate hydrolysis by fluorimetric assay
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Prolyl endopeptidase
(Homo sapiens (Human))
Mcgill University
Curated by
ChEMBL
Ligand
BDBM50312222
(CHEMBL1079579 | N-Benzyloxycarbonylamino-glycine-2...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 95nM
Assay Description:
Inhibition of prolyl oligopeptidase in human HCEC cell extracts assessed as blockade of Z-Gly-Pro-AMC substrate hydrolysis by fluorimetric assay
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Prolyl endopeptidase
(Homo sapiens (Human))
Mcgill University
Curated by
ChEMBL
Ligand
BDBM50312222
(CHEMBL1079579 | N-Benzyloxycarbonylamino-glycine-2...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 180nM
Assay Description:
Inhibition of prolyl oligopeptidase in intact human HCEC cells assessed as blockade of Z-Gly-Pro-AMC substrate hydrolysis by fluorimetric assay
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Prolyl endopeptidase
(Homo sapiens (Human))
Mcgill University
Curated by
ChEMBL
Ligand
BDBM50312222
(CHEMBL1079579 | N-Benzyloxycarbonylamino-glycine-2...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 325nM
Assay Description:
Inhibition of prolyl oligopeptidase in intact human LN229 cells assessed as blockade of Z-Gly-Pro-AMC substrate hydrolysis by fluorimetric assay
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Prolyl endopeptidase
(Homo sapiens (Human))
Mcgill University
Curated by
ChEMBL
Ligand
BDBM50312222
(CHEMBL1079579 | N-Benzyloxycarbonylamino-glycine-2...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 590nM
Assay Description:
Inhibition of prolyl oligopeptidase in intact human LNZ308 cells assessed as blockade of Z-Gly-Pro-AMC substrate hydrolysis by fluorimetric assay
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI