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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
4
hits in this display
Target
Histamine H3 receptor
(Homo sapiens (Human))
Jagiellonian University Medical College
Curated by
ChEMBL
Ligand
BDBM50343847
(3-(1H-Imidazol-4-yl)propyl2-cyclohexylpropylcarbam...)
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Affinity Data
Ki: 86nM
Assay Description:
Displacement of [125I]iodoproxyfan from human histamine H3 receptor expressed in CHO-K1 cells after 60 mins by gamma counting
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
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In Depth
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Article
PubMed
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Target
Histamine H4 receptor
(Homo sapiens (Human))
Jagiellonian University Medical College
Curated by
ChEMBL
Ligand
BDBM50343847
(3-(1H-Imidazol-4-yl)propyl2-cyclohexylpropylcarbam...)
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Affinity Data
Ki: 447nM
Assay Description:
Displacement of [3H]histamine from human histamine H4 receptor expressed in Sf9 cells co-expressing Galphai2 and Gbeta1gamma2 subunit after 60 mins b...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Histamine H3 receptor
(GUINEA PIG)
Jagiellonian University Medical College
Curated by
ChEMBL
Ligand
BDBM50343847
(3-(1H-Imidazol-4-yl)propyl2-cyclohexylpropylcarbam...)
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Affinity Data
IC50: 43nM
Assay Description:
Antagonist activity against histamine H3 receptor in guinea pig ileum assessed as inhibition of electrically-evoked twitches after 30 mins in presenc...
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Histamine H1 receptor
(Cavia porcellus (domestic guinea pig))
Jagiellonian University Medical College
Curated by
ChEMBL
Ligand
BDBM50343847
(3-(1H-Imidazol-4-yl)propyl2-cyclohexylpropylcarbam...)
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Affinity Data
Kd: 1.07E+4nM
Assay Description:
Antagonist activity at histamine H1 receptor in guinea-pig ileum
More data for this Ligand-Target Pair
Target Info
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI