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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
9
hits in this display
Target
5-hydroxytryptamine receptor 4
(GUINEA PIG)
Pfizer
Curated by
ChEMBL
Ligand
BDBM50181840
((1R,7aS)-hexahydro-1H-pyrrolizin-1-ylmethyl 1-Meth...)
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Affinity Data
Ki: 0.183nM
Assay Description:
Displacement of [3H]GR-113808 from 5HT4 receptor in guinea pig striatum
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
5-hydroxytryptamine receptor 3A/3B
(Rattus norvegicus)
Pfizer
Curated by
ChEMBL
Ligand
BDBM50181840
((1R,7aS)-hexahydro-1H-pyrrolizin-1-ylmethyl 1-Meth...)
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Affinity Data
Ki: 5nM
Assay Description:
Displacement of [3H]GR65630 from 5HT3 receptor in brain cortex from Wistar rat
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Serotonin 2 (5-HT2) receptor
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50181840
((1R,7aS)-hexahydro-1H-pyrrolizin-1-ylmethyl 1-Meth...)
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Affinity Data
IC50: >1.00E+4nM
Assay Description:
Binding affinity to 5HT2 receptor
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50181840
((1R,7aS)-hexahydro-1H-pyrrolizin-1-ylmethyl 1-Meth...)
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Affinity Data
IC50: >1.00E+4nM
Assay Description:
Binding affinity to adrenergic alpha-1 receptor
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
D(2) dopamine receptor
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50181840
((1R,7aS)-hexahydro-1H-pyrrolizin-1-ylmethyl 1-Meth...)
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Copy InChI
Affinity Data
IC50: >1.00E+4nM
Assay Description:
Binding affinity to dopamine receptor D2
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(1A) dopamine receptor
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50181840
((1R,7aS)-hexahydro-1H-pyrrolizin-1-ylmethyl 1-Meth...)
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Copy InChI
Affinity Data
IC50: >1.00E+4nM
Assay Description:
Binding affinity to dopamine receptor D1
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Beta-2 adrenergic receptor
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50181840
((1R,7aS)-hexahydro-1H-pyrrolizin-1-ylmethyl 1-Meth...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+4nM
Assay Description:
Binding affinity to adrenergic beta-2 receptor
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Beta-1 adrenergic receptor
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50181840
((1R,7aS)-hexahydro-1H-pyrrolizin-1-ylmethyl 1-Meth...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+4nM
Assay Description:
Binding affinity to adrenergic beta-1 receptor
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Alpha-2A/Alpha-2B/Alpha-2C adrenergic receptor
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50181840
((1R,7aS)-hexahydro-1H-pyrrolizin-1-ylmethyl 1-Meth...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+4nM
Assay Description:
Binding affinity to adrenergic alpha-2 receptor
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI