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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
4
hits in this display
Target
Neuronal acetylcholine receptor subunit alpha-7
(Rattus norvegicus (Rat))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50296748
(CHEMBL564850 | naphthalen-2-yl 1,4-diazabicyclo[3....)
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Affinity Data
Ki: 23nM
Assay Description:
Displacement of [125I]BTX from rat alpha7 nAChR expressed in rat GH4C1 cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
5-hydroxytryptamine receptor 3A
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50296748
(CHEMBL564850 | naphthalen-2-yl 1,4-diazabicyclo[3....)
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Affinity Data
IC50: >3.16E+3nM
Assay Description:
Displacement of [3H]LY278584 from human 5HT3 receptor expressed in HEK293 cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Neuronal acetylcholine receptor subunit alpha-3
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50296748
(CHEMBL564850 | naphthalen-2-yl 1,4-diazabicyclo[3....)
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Affinity Data
IC50: 4.91E+3nM
Assay Description:
Displacement of [3H]epibatidine from alpha3 nAChR in human IMR32 cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Neuronal acetylcholine receptor subunit alpha-4
(Rattus norvegicus (Rat))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50296748
(CHEMBL564850 | naphthalen-2-yl 1,4-diazabicyclo[3....)
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Copy InChI
Affinity Data
IC50: 9.88E+3nM
Assay Description:
Displacement of L-[3H]Nicotine from alpha4beta2 nAChR in rat brain homogenate by rapid filtration method
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI