Home
About
Info
Download
WebServices
Contact
Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
6
hits in this display
Target
Neuronal acetylcholine receptor subunit alpha-7
(Rattus norvegicus (Rat))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50296730
(CHEMBL563848 | phenyl 1,4-diazabicyclo[3.2.2]nonan...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 739nM
Assay Description:
Displacement of [125I]BTX from rat alpha7 nicotinic acetylcholine receptor expressed in GH4C1 cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Neuronal acetylcholine receptor subunit alpha-7
(Homo sapiens (Human))
Targacept
Curated by
ChEMBL
Ligand
BDBM50296730
(CHEMBL563848 | phenyl 1,4-diazabicyclo[3.2.2]nonan...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 739nM
Assay Description:
Binding affinity to alpha7 nAChR
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Neuronal acetylcholine receptor subunit alpha-7
(Rattus norvegicus (Rat))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50296730
(CHEMBL563848 | phenyl 1,4-diazabicyclo[3.2.2]nonan...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 739nM
Assay Description:
Displacement of [125I]BTX from rat alpha7 nAChR expressed in rat GH4C1 cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 3A
(Homo sapiens (Human))
Targacept
Curated by
ChEMBL
Ligand
BDBM50296730
(CHEMBL563848 | phenyl 1,4-diazabicyclo[3.2.2]nonan...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 3.99E+3nM
Assay Description:
Binding affinity to 5HT3 receptor
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 3A
(Mus musculus (house mouse))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50296730
(CHEMBL563848 | phenyl 1,4-diazabicyclo[3.2.2]nonan...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 3.99E+3nM
Assay Description:
Displacement of [3H]LY278584 from mouse 5HT3 receptor expressed in HEK293 cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Neuronal acetylcholine receptor subunit alpha-4
(Rattus norvegicus (Rat))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50296730
(CHEMBL563848 | phenyl 1,4-diazabicyclo[3.2.2]nonan...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.04E+3nM
Assay Description:
Displacement of L-[3H]Nicotine from alpha4beta2 nAChR in rat brain homogenate by rapid filtration method
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI