Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetCaspase-3(Homo sapiens (Human))
Burnham Institute

LigandBDBM10218(BI-9C3 | Burnham Institute Compound 4 | phenyl 2-(...)Copy SMILESCopy InChI

Affinity DataIC50:  4.00E+4nMpH: 7.5 T: 2°CAssay Description:Fluorescent assays were carried out in black 96-well plates. Caspase activity was monitored using a Labsystem Fluoroskan II spectrofluorometer with a...More data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPurchasePC cidPC sidPatentsSimilars

In DepthDetails ArticlePubMed
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TargetCaspase-8(Homo sapiens (Human))
Burnham Institute

LigandBDBM10218(BI-9C3 | Burnham Institute Compound 4 | phenyl 2-(...)Copy SMILESCopy InChI

Affinity DataIC50:  6.00E+4nMAssay Description:Fluorescent assays were carried out in black 96-well plates. Caspase activity was monitored using a Labsystem Fluoroskan II spectrofluorometer with a...More data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoPurchasePC cidPC sidPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetCaspase-7(Homo sapiens (Human))
Burnham Institute

LigandBDBM10218(BI-9C3 | Burnham Institute Compound 4 | phenyl 2-(...)Copy SMILESCopy InChI

Affinity DataIC50: >2.00E+5nMAssay Description:Fluorescent assays were carried out in black 96-well plates. Caspase activity was monitored using a Labsystem Fluoroskan II spectrofluorometer with a...More data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPurchasePC cidPC sidPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI