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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
9
hits in this display
Target
5-hydroxytryptamine receptor 1A
(Rattus norvegicus (rat))
TBA
Curated by
ChEMBL
Ligand
BDBM50164450
((S)-2-(4-Naphthalen-1-yl-piperazin-1-ylmethyl)-hex...)
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Affinity Data
Ki: 4.10nM
Assay Description:
In vitro inhibition of [3H]8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor in rat cerebral cortex membranes
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
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Article
PubMed
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Target
5-hydroxytryptamine receptor 3A
(RAT)
TBA
Curated by
ChEMBL
Ligand
BDBM50164450
((S)-2-(4-Naphthalen-1-yl-piperazin-1-ylmethyl)-hex...)
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Affinity Data
Ki: 8.90nM
Assay Description:
In vitro inhibition of [3H]LY-278584 binding to 5-hydroxytryptamine 3 receptor in rat cerebral cortex membranes
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
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GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
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In Depth
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Article
PubMed
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Target
5-hydroxytryptamine receptor 2A
(Rattus norvegicus (rat))
TBA
Curated by
ChEMBL
Ligand
BDBM50164450
((S)-2-(4-Naphthalen-1-yl-piperazin-1-ylmethyl)-hex...)
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Affinity Data
Ki: 14nM
Assay Description:
In vitro inhibition of [3H]ketanserin binding to 5-hydroxytryptamine 2A receptor in rat cerebral frontal cortex membranes
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
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GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
5-hydroxytryptamine receptor 7
(Rattus norvegicus (rat))
TBA
Curated by
ChEMBL
Ligand
BDBM50164450
((S)-2-(4-Naphthalen-1-yl-piperazin-1-ylmethyl)-hex...)
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Affinity Data
Ki: 101nM
Assay Description:
In vitro inhibition of [3H]5-CT binding to 5-hydroxytryptamine 7 receptor in rat hyphalamus membranes
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
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Ligand Info
CHEMBL
PC cid
PC sid
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In Depth
Details
Article
PubMed
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Target
D(2) dopamine receptor
(Rattus norvegicus (rat))
TBA
Curated by
ChEMBL
Ligand
BDBM50164450
((S)-2-(4-Naphthalen-1-yl-piperazin-1-ylmethyl)-hex...)
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Affinity Data
Ki: 192nM
Assay Description:
In vitro inhibition of [3H]-raclopride binding to Dopamine receptor D2 in rat striatum membranes
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
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Ligand Info
CHEMBL
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In Depth
Details
Article
PubMed
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Target
Sodium-dependent serotonin transporter
(Rattus norvegicus (rat))
TBA
Curated by
ChEMBL
Ligand
BDBM50164450
((S)-2-(4-Naphthalen-1-yl-piperazin-1-ylmethyl)-hex...)
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Affinity Data
Ki: 976nM
Assay Description:
In vitro inhibition of [3H]paroxetine binding to 5-hydroxytryptamine transporter in rat cerebral cortex membranes
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
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GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
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Article
PubMed
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Target
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor
(Rattus norvegicus (rat))
TBA
Curated by
ChEMBL
Ligand
BDBM50164450
((S)-2-(4-Naphthalen-1-yl-piperazin-1-ylmethyl)-hex...)
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Affinity Data
Ki: >1.00E+3nM
Assay Description:
In vitro inhibition of [3H]prazosin binding to Alpha-1 adrenergic receptor in rat cerebral cortex membranes
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
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Ligand Info
CHEMBL
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PC sid
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In Depth
Details
Article
PubMed
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Target
5-hydroxytryptamine receptor 4
(RAT)
TBA
Curated by
ChEMBL
Ligand
BDBM50164450
((S)-2-(4-Naphthalen-1-yl-piperazin-1-ylmethyl)-hex...)
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Affinity Data
Ki: >1.00E+3nM
Assay Description:
In vitro inhibition of [3H]GR-113808 binding to 5-hydroxytryptamine 4 receptor of rat striatum membranes
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
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In Depth
Details
Article
PubMed
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Target
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human))
TBA
Curated by
ChEMBL
Ligand
BDBM50164450
((S)-2-(4-Naphthalen-1-yl-piperazin-1-ylmethyl)-hex...)
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Affinity Data
EC50: 150nM
Assay Description:
Inhibition of forskolin-induced increase in cAMP in human 5-hydroxytryptamine 1A receptor expressed HeLa cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI