Home
About
Info
Download
WebServices
Contact
Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
12
hits in this display
Target
5-hydroxytryptamine receptor 3A
(Homo sapiens (Human))
University Of Modena And Reggio Emilia
Curated by
ChEMBL
Ligand
BDBM50417287
(Aloxi | Aurothioglucose | PALONOSETRON | PALONOSET...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 0.0316nM
Assay Description:
Binding affinity to 5HT3A receptor
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
MCE
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
PDB
3D Structure (crystal)
Copy BDB DOI
Target
5-hydroxytryptamine receptor 3A/3B
(Rattus norvegicus)
Syntex Research
Curated by
ChEMBL
Ligand
BDBM50417287
(Aloxi | Aurothioglucose | PALONOSETRON | PALONOSET...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 0.0400nM
Assay Description:
Binding affinity against 5-hydroxytryptamine 3 (5-HT3) receptor in rat brain cortical membranes using radioligand [3H]quipazine
Checked by Author
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
MCE
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
PDB
3D Structure (crystal)
Copy BDB DOI
Target
5-hydroxytryptamine receptor 3A
(Homo sapiens (Human))
University Of Modena And Reggio Emilia
Curated by
ChEMBL
Ligand
BDBM50417287
(Aloxi | Aurothioglucose | PALONOSETRON | PALONOSET...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 0.830nM
Assay Description:
Antagonist activity at human wild type 5-HT3A receptor expressed in HEK293 cells assessed as inhibition of 5-HT-induced response after 45 mins by FLI...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
MCE
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
PDB
3D Structure (crystal)
Copy BDB DOI
Target
5-hydroxytryptamine receptor 3A/3B
(Homo sapiens (Human))
Universit£
Curated by
ChEMBL
Ligand
BDBM50417287
(Aloxi | Aurothioglucose | PALONOSETRON | PALONOSET...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 0.880nM
Assay Description:
Antagonist activity at human wild type 5-HT3A/5-HT3B receptor expressed in HEK293 cells assessed as inhibition of 5-HT-induced response after 45 mins...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
Purchase
MCE
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
PDB
3D Structure (crystal)
Copy BDB DOI
Target
5-hydroxytryptamine receptor 3A
(Homo sapiens (Human))
University Of Modena And Reggio Emilia
Curated by
ChEMBL
Ligand
BDBM50417287
(Aloxi | Aurothioglucose | PALONOSETRON | PALONOSET...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.70nM
Assay Description:
Antagonist activity at human 5-HT3 receptor expressed in CHO-K1 cells assessed as inhibition of 5-HT induced inward currents preincubated for 30 sec ...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
MCE
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human))
University Of Oxford
Curated by
ChEMBL
Ligand
BDBM50417287
(Aloxi | Aurothioglucose | PALONOSETRON | PALONOSET...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2.00E+3nM
Assay Description:
Inhibition of rapid delayed inward rectifying potassium current (IKr) in Chinese hamster ovary (CHO) K1 cells stably expressing hERG measured using I...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
MCE
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human))
University Of Oxford
Curated by
ChEMBL
Ligand
BDBM50417287
(Aloxi | Aurothioglucose | PALONOSETRON | PALONOSET...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 3.98E+3nM
Assay Description:
Inhibition of transient outward potassium current (Ito) current in Chinese Hamster Ovary (CHO) K1 cells expressing human Kv4.3 measured using IonWork...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
MCE
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Sodium channel protein type 5 subunit alpha
(Homo sapiens (Human))
University Of Oxford
Curated by
ChEMBL
Ligand
BDBM50417287
(Aloxi | Aurothioglucose | PALONOSETRON | PALONOSET...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2.00E+4nM
Assay Description:
Inhibition of transient outward potassium current (Ito) current in Chinese Hamster Ovary (CHO) K1 cells expressing human Kv4.3 measured using IonWork...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
MCE
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Potassium voltage-gated channel subfamily E/KQT member 1
(Homo sapiens (Human))
University Of Oxford
Curated by
ChEMBL
Ligand
BDBM50417287
(Aloxi | Aurothioglucose | PALONOSETRON | PALONOSET...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 5.01E+4nM
Assay Description:
Inhibition of slow delayed inward rectifying potassium current (Iks) in Chinese Hamster Ovary (CHO) cells expressing hKvLQT1/hminK measured using Ion...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
Purchase
MCE
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Voltage-dependent L-type calcium channel subunit alpha-1C
(Homo sapiens (Human))
University Of Oxford
Curated by
ChEMBL
Ligand
BDBM50417287
(Aloxi | Aurothioglucose | PALONOSETRON | PALONOSET...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 3.98E+5nM
Assay Description:
Inhibition of long-lasting type calcium current (hICa) in Chinese Hamster Ovary (CHO) cells expressing hCav1.2 measured using IonWorks Quattro automa...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
MCE
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 3A/3B
(Homo sapiens (Human))
Universit£
Curated by
ChEMBL
Ligand
BDBM50417287
(Aloxi | Aurothioglucose | PALONOSETRON | PALONOSET...)
Copy SMILES
Copy InChI
Affinity Data
Kd: 0.180nM
Assay Description:
Binding affinity to human wild type 5-HT3A/5-HT3B receptor expressed in HEK293 cells after 24 hrs by liquid scintillation counting analysis
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
Purchase
MCE
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
PDB
3D Structure (crystal)
Copy BDB DOI
Target
5-hydroxytryptamine receptor 3A
(Homo sapiens (Human))
University Of Modena And Reggio Emilia
Curated by
ChEMBL
Ligand
BDBM50417287
(Aloxi | Aurothioglucose | PALONOSETRON | PALONOSET...)
Copy SMILES
Copy InChI
Affinity Data
Kd: 0.320nM
Assay Description:
Binding affinity to human wild type 5-HT3A receptor expressed in HEK293 cells after 24 hrs by liquid scintillation counting analysis
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
MCE
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
PDB
3D Structure (crystal)
Copy BDB DOI