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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
9
hits in this display
Target
5-hydroxytryptamine receptor 3A
(Homo sapiens (Human))
Amri
Curated by
ChEMBL
Ligand
BDBM50014556
(CHEMBL3261486 | US9045501, 25)
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Affinity Data
Ki: 5.70nM
Assay Description:
Displacement of [9-methyl-3H]BRL-43694 from human 5-HT3A receptor after overnight incubation by scintillation proximity assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
5-hydroxytryptamine receptor 3A
(Homo sapiens (Human))
Amri
Curated by
ChEMBL
Ligand
BDBM50014556
(CHEMBL3261486 | US9045501, 25)
Copy SMILES
Copy InChI
Affinity Data
Ki: 7nM ΔG°: -46.5kJ/mole
pH: 7.5 T: 2°C
Assay Description:
The relative affinity of the various compounds for the human 5-HT3 receptor was measured in a radioligand binding assay, using a scintillation proxim...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
US Patent
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Target
Cytochrome P450 2B6
(Homo sapiens (Human))
Amri
Curated by
ChEMBL
Ligand
BDBM50014556
(CHEMBL3261486 | US9045501, 25)
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Affinity Data
IC50: >5.00E+4nM
Assay Description:
Inhibition of CYP2B6 (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Cytochrome P450 1A2
(Homo sapiens (Human))
Amri
Curated by
ChEMBL
Ligand
BDBM50014556
(CHEMBL3261486 | US9045501, 25)
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Affinity Data
IC50: >5.00E+4nM
Assay Description:
Inhibition of CYP1A2 (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cytochrome P450 3A4
(Homo sapiens (Human))
Amri
Curated by
ChEMBL
Ligand
BDBM50014556
(CHEMBL3261486 | US9045501, 25)
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Affinity Data
IC50: >5.00E+4nM
Assay Description:
Inhibition of CYP3A4 (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cytochrome P450 2C9
(Homo sapiens (Human))
Amri
Curated by
ChEMBL
Ligand
BDBM50014556
(CHEMBL3261486 | US9045501, 25)
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Copy InChI
Affinity Data
IC50: >5.00E+4nM
Assay Description:
Inhibition of CYP2C9 (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cytochrome P450 2C19
(Homo sapiens (Human))
Amri
Curated by
ChEMBL
Ligand
BDBM50014556
(CHEMBL3261486 | US9045501, 25)
Copy SMILES
Copy InChI
Affinity Data
IC50: >5.00E+4nM
Assay Description:
Inhibition of CYP2C19 (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cytochrome P450 2D6
(Homo sapiens (Human))
Amri
Curated by
ChEMBL
Ligand
BDBM50014556
(CHEMBL3261486 | US9045501, 25)
Copy SMILES
Copy InChI
Affinity Data
IC50: >5.00E+4nM
Assay Description:
Inhibition of CYP2D6 (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 3A
(Homo sapiens (Human))
Amri
Curated by
ChEMBL
Ligand
BDBM50014556
(CHEMBL3261486 | US9045501, 25)
Copy SMILES
Copy InChI
Affinity Data
EC50: 178nM
Assay Description:
Agonist activity at human 5-HT3A receptor expressed in HEK293 cells in presence of carbachol
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI