Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Amri

Curated by ChEMBL

LigandBDBM50014547(CHEMBL3261478 | US9045501, 1)Copy SMILESCopy InChI

Affinity DataKi:  68nMAssay Description:Displacement of [9-methyl-3H]BRL-43694 from human 5-HT3A receptor after overnight incubation by scintillation proximity assayMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Amri

Curated by ChEMBL

LigandBDBM50014547(CHEMBL3261478 | US9045501, 1)Copy SMILESCopy InChI

Affinity DataKi:  74nM ΔG°:  -40.7kJ/molepH: 7.5 T: 2°CAssay Description:The relative affinity of the various compounds for the human 5-HT3 receptor was measured in a radioligand binding assay, using a scintillation proxim...More data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails US Patent
Copy BDB DOI