Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 7 hits in this display   

TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Tianjin University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM29569(acs.jmedchem.1c00409_ST.540 | isatin sulfonamide, ...)
Affinity DataIC50:  1.27E+4nMAssay Description:Inhibition of GST-tagged SARS coronavirus 3C-like protease by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Tianjin University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM29569(acs.jmedchem.1c00409_ST.540 | isatin sulfonamide, ...)
Affinity DataIC50:  1.27E+4nMAssay Description:This is a review article. Please point to the original journal.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Washington University

LigandPNGBDBM29569(acs.jmedchem.1c00409_ST.540 | isatin sulfonamide, ...)
Affinity DataIC50: >2.00E+4nMAssay Description:The caspase enzymatic activity was determined by measuring the accumulation of a fluorogenic product. All assays were prepared in 96-well format. Rec...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-6(Homo sapiens (Human))
Washington University

LigandPNGBDBM29569(acs.jmedchem.1c00409_ST.540 | isatin sulfonamide, ...)
Affinity DataIC50: >2.00E+4nMAssay Description:The caspase enzymatic activity was determined by measuring the accumulation of a fluorogenic product. All assays were prepared in 96-well format. Rec...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-7(Homo sapiens (Human))
Washington University

LigandPNGBDBM29569(acs.jmedchem.1c00409_ST.540 | isatin sulfonamide, ...)
Affinity DataIC50: >2.00E+4nMAssay Description:The caspase enzymatic activity was determined by measuring the accumulation of a fluorogenic product. All assays were prepared in 96-well format. Rec...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Washington University

LigandPNGBDBM29569(acs.jmedchem.1c00409_ST.540 | isatin sulfonamide, ...)
Affinity DataIC50: >2.50E+4nMpH: 7.4 T: 2°CAssay Description:The caspase enzymatic activity was determined by measuring the accumulation of a fluorogenic product. All assays were prepared in 96-well format. Rec...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-8(Homo sapiens (Human))
Washington University

LigandPNGBDBM29569(acs.jmedchem.1c00409_ST.540 | isatin sulfonamide, ...)
Affinity DataIC50: >5.00E+4nMpH: 7.4 T: 2°CAssay Description:The caspase enzymatic activity was determined by measuring the accumulation of a fluorogenic product. All assays were prepared in 96-well format. Rec...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed