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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 5 hits in this display   

TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50433916(PS653 ('1,6-dihydrodibenzo[c,d,g]indazol-6-one...)
Affinity DataIC50:  40nMAssay Description:Inhibition of human JNK1Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50433916(PS653 ('1,6-dihydrodibenzo[c,d,g]indazol-6-one...)
Affinity DataIC50:  40nMAssay Description:Inhibition of human JNK2Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50433916(PS653 ('1,6-dihydrodibenzo[c,d,g]indazol-6-one...)
Affinity DataIC50:  90nMAssay Description:Inhibition of human JNK3Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Shionogi Pharmaceutical Research Center

Curated by ChEMBL
LigandPNGBDBM50433916(PS653 ('1,6-dihydrodibenzo[c,d,g]indazol-6-one...)
Affinity DataIC50:  98nMAssay Description:Inhibition of MPS1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-phosphoinositide-dependent protein kinase 1 [50-359](Homo sapiens (Human))
Universitätsklinikum Frankfurt

LigandPNGBDBM50433916(PS653 ('1,6-dihydrodibenzo[c,d,g]indazol-6-one...)
Affinity DataKd:  1.25E+3nMpH: 7.4Assay Description:Titrations were performed by a 0.4 µl injection followed by 19 successive injections (2 µl) of each compound(adenosine 500 µM, PS653 250 µM) into a 2...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed