Compile Data Set for Download or QSAR
maximum 50k data

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 4 hits in this display   

TargetCytochrome P450 1B1(Homo sapiens (Human))
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM50159612(2-Pyridin-4-yl-benzo[h]chromen-4-one | 4-(4-Oxo-4H...)
Affinity DataIC50:  9.30nMAssay Description:Inhibition of human recombinant CYP1B1 using 7-ethoxyresorufin as substrate in presence of glucose-6-phosphate, glucose-6-phosphate dehydrogenase and...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A1(Homo sapiens (Human))
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM50159612(2-Pyridin-4-yl-benzo[h]chromen-4-one | 4-(4-Oxo-4H...)
Affinity DataIC50:  19nMAssay Description:Inhibition of human recombinant CYP1A1 using 7-ethoxyresorufin as substrate in presence of glucose-6-phosphate, glucose-6-phosphate dehydrogenase and...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM50159612(2-Pyridin-4-yl-benzo[h]chromen-4-one | 4-(4-Oxo-4H...)
Affinity DataIC50:  36nMAssay Description:Inhibition of human recombinant CYP1A2 using 7-ethoxyresorufin as substrate in presence of glucose-6-phosphate, glucose-6-phosphate dehydrogenase and...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50159612(2-Pyridin-4-yl-benzo[h]chromen-4-one | 4-(4-Oxo-4H...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of DNA dependent protein kinase isolated from HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed