Home
About
Info
Download
WebServices
Contact
Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
73
hits in this display
Target
Carbonic anhydrase 14
(Homo sapiens (Human))
Universita Degli Studi Di Firenze
Curated by
ChEMBL
Ligand
BDBM12342
(2H-chromen-2-one | CHEMBL6466 | Coumarin)
Copy SMILES
Copy InChI
Affinity Data
Ki: 48nM
Assay Description:
Inhibition of human carbonic anhydrase 14 by stopped flow CO2 hydration assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
KEGG
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Zn finger protein
(Nicotiana tabacum)
Università
Curated by
ChEMBL
Ligand
BDBM12342
(2H-chromen-2-one | CHEMBL6466 | Coumarin)
Copy SMILES
Copy InChI
Affinity Data
Ki: >100nM
Assay Description:
Inhibition of human recombinant CA12 catalytic domain by stopped-flow CO2 hydration method
More data for this Ligand-Target Pair
Target Info
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
KEGG
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Carbonic anhydrase 9
(Homo sapiens (Human))
Università
Curated by
ChEMBL
Ligand
BDBM12342
(2H-chromen-2-one | CHEMBL6466 | Coumarin)
Copy SMILES
Copy InChI
Affinity Data
Ki: >100nM
Assay Description:
Inhibition of human recombinant CA9 catalytic domain by stopped-flow CO2 hydration method
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
KEGG
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Carbonic anhydrase 6
(Homo sapiens (Human))
Universita Degli Studi Di Firenze
Curated by
ChEMBL
Ligand
BDBM12342
(2H-chromen-2-one | CHEMBL6466 | Coumarin)
Copy SMILES
Copy InChI
Affinity Data
Ki: 2.00E+3nM
Assay Description:
Inhibition of human carbonic anhydrase 6 by stopped flow CO2 hydration assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
KEGG
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Carbonic anhydrase 1
(Homo sapiens (Human))
Universita Degli Studi Di Firenze
Curated by
ChEMBL
Ligand
BDBM12342
(2H-chromen-2-one | CHEMBL6466 | Coumarin)
Copy SMILES
Copy InChI
Affinity Data
Ki: 3.10E+3nM
Assay Description:
Inhibition of human carbonic anhydrase 1 by stopped flow CO2 hydration assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
KEGG
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Carbonic anhydrase 1
(Homo sapiens (Human))
Universita Degli Studi Di Firenze
Curated by
ChEMBL
Ligand
BDBM12342
(2H-chromen-2-one | CHEMBL6466 | Coumarin)
Copy SMILES
Copy InChI
Affinity Data
Ki: 3.10E+3nM
Assay Description:
Inhibition of full length human CA1 cytosolic isoform by stopped-flow CO2 hydration method
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
KEGG
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Carbonic anhydrase 1
(Homo sapiens (Human))
Universita Degli Studi Di Firenze
Curated by
ChEMBL
Ligand
BDBM12342
(2H-chromen-2-one | CHEMBL6466 | Coumarin)
Copy SMILES
Copy InChI
Affinity Data
Ki: 3.10E+3nM
Assay Description:
Inhibition of full length human recombinant CA1 cytosolic isoform after 6 hrs by stopped-flow CO2 hydration method
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
KEGG
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Carbonic anhydrase 1
(Homo sapiens (Human))
Universita Degli Studi Di Firenze
Curated by
ChEMBL
Ligand
BDBM12342
(2H-chromen-2-one | CHEMBL6466 | Coumarin)
Copy SMILES
Copy InChI
Affinity Data
Ki: 3.10E+3nM
Assay Description:
Inhibition of human CA1 pre-incubated for 15 mins to 24 hrs measured after 6 hrs by phenol red-based stopped-flow CO2 hydrase assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
KEGG
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Carbonic anhydrase 1
(Homo sapiens (Human))
Universita Degli Studi Di Firenze
Curated by
ChEMBL
Ligand
BDBM12342
(2H-chromen-2-one | CHEMBL6466 | Coumarin)
Copy SMILES
Copy InChI
Affinity Data
Ki: 3.10E+3nM
Assay Description:
Inhibition of human carbonic anhydrase 1 preincubated for 6 hrs by CO2 hydration stopped-flow assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
KEGG
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Carbonic anhydrase 1
(Homo sapiens (Human))
Universita Degli Studi Di Firenze
Curated by
ChEMBL
Ligand
BDBM12342
(2H-chromen-2-one | CHEMBL6466 | Coumarin)
Copy SMILES
Copy InChI
Affinity Data
Ki: 3.10E+3nM
Assay Description:
Inhibition of human carbonic anhydrase 1 after 6 hrs by stop-flow CO2 hydration assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
KEGG
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Carbonic anhydrase 1
(Homo sapiens (Human))
Universita Degli Studi Di Firenze
Curated by
ChEMBL
Ligand
BDBM12342
(2H-chromen-2-one | CHEMBL6466 | Coumarin)
Copy SMILES
Copy InChI
Affinity Data
Ki: 3.10E+3nM
Assay Description:
Inhibition of human recombinant carbonic anhydrase 1 preincubated for 15 mins to 72 hrs measured after 6 hrs by stopped flow CO2 hydration method
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
KEGG
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Carbonic anhydrase 1
(Homo sapiens (Human))
Universita Degli Studi Di Firenze
Curated by
ChEMBL
Ligand
BDBM12342
(2H-chromen-2-one | CHEMBL6466 | Coumarin)
Copy SMILES
Copy InChI
Affinity Data
Ki: 3.10E+3nM
Assay Description:
Inhibition of human carbonic anhydrase 1 by Stopped-Flow CO2 Hydrase assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
KEGG
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Carbonic anhydrase 1
(Homo sapiens (Human))
Universita Degli Studi Di Firenze
Curated by
ChEMBL
Ligand
BDBM12342
(2H-chromen-2-one | CHEMBL6466 | Coumarin)
Copy SMILES
Copy InChI
Affinity Data
Ki: 3.10E+3nM
Assay Description:
Inhibition of human full-length cytosolic CA1 after 6 hrs by stopped flow CO2 hydration assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
KEGG
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Carbonic anhydrase 7
(Homo sapiens (Human))
Universita Degli Studi Di Firenze
Curated by
ChEMBL
Ligand
BDBM12342
(2H-chromen-2-one | CHEMBL6466 | Coumarin)
Copy SMILES
Copy InChI
Affinity Data
Ki: 3.30E+3nM
Assay Description:
Inhibition of human carbonic anhydrase 7 by stopped flow CO2 hydration assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
KEGG
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Induced myeloid leukemia cell differentiation protein Mcl-1
(Homo sapiens (Human))
Dalian University Of Technology
Curated by
ChEMBL
Ligand
BDBM12342
(2H-chromen-2-one | CHEMBL6466 | Coumarin)
Copy SMILES
Copy InChI
Affinity Data
Ki: 4.06E+3nM
Assay Description:
Displacement of FAM-Bid peptide from recombinant N-terminal His6x-tagged human Mcl-1 expressed in Escherichia coli BL21 (DE3) incubated for 30 mins b...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
KEGG
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Carbonic anhydrase 5B, mitochondrial
(Homo sapiens (Human))
Universita Degli Studi Di Firenze
Curated by
ChEMBL
Ligand
BDBM12342
(2H-chromen-2-one | CHEMBL6466 | Coumarin)
Copy SMILES
Copy InChI
Affinity Data
Ki: 5.20E+3nM
Assay Description:
Inhibition of human carbonic anhydrase 5B by stopped flow CO2 hydration assay
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
KEGG
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Carbonic anhydrase 3
(Homo sapiens (Human))
Universita Degli Studi Di Firenze
Curated by
ChEMBL
Ligand
BDBM12342
(2H-chromen-2-one | CHEMBL6466 | Coumarin)
Copy SMILES
Copy InChI
Affinity Data
Ki: 5.60E+3nM
Assay Description:
Inhibition of human carbonic anhydrase 3 by stopped flow CO2 hydration assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
KEGG
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Carbonic anhydrase 4
(Homo sapiens (Human))
Universita Degli Studi Di Firenze
Curated by
ChEMBL
Ligand
BDBM12342
(2H-chromen-2-one | CHEMBL6466 | Coumarin)
Copy SMILES
Copy InChI
Affinity Data
Ki: 6.80E+3nM
Assay Description:
Inhibition of human carbonic anhydrase 4 by stopped flow CO2 hydration assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
KEGG
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Carbonic anhydrase 12
(Homo sapiens (Human))
Universita Degli Studi Di Firenze
Curated by
ChEMBL
Ligand
BDBM12342
(2H-chromen-2-one | CHEMBL6466 | Coumarin)
Copy SMILES
Copy InChI
Affinity Data
Ki: 8.90E+3nM
Assay Description:
Inhibition of human carbonic anhydrase 12 by stopped flow CO2 hydration assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
KEGG
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Carbonic anhydrase 9
(Homo sapiens (Human))
Università
Curated by
ChEMBL
Ligand
BDBM12342
(2H-chromen-2-one | CHEMBL6466 | Coumarin)
Copy SMILES
Copy InChI
Affinity Data
Ki: 9.10E+3nM
Assay Description:
Inhibition of human carbonic anhydrase 9 by stopped flow CO2 hydration assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
KEGG
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Carbonic anhydrase 13
(Mus musculus (mouse))
Universita Degli Studi Di Firenze
Curated by
ChEMBL
Ligand
BDBM12342
(2H-chromen-2-one | CHEMBL6466 | Coumarin)
Copy SMILES
Copy InChI
Affinity Data
Ki: 9.20E+3nM
Assay Description:
Inhibition of mouse carbonic anhydrase 13 by stopped flow CO2 hydration assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
KEGG
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Carbonic anhydrase 2
(Homo sapiens (Human))
Latvian Association Of Human Genetics
Curated by
ChEMBL
Ligand
BDBM12342
(2H-chromen-2-one | CHEMBL6466 | Coumarin)
Copy SMILES
Copy InChI
Affinity Data
Ki: 9.20E+3nM
Assay Description:
Inhibition of full length human recombinant CA2 cytosolic isoform after 6 hrs by stopped-flow CO2 hydration method
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
KEGG
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Carbonic anhydrase 2
(Homo sapiens (Human))
Latvian Association Of Human Genetics
Curated by
ChEMBL
Ligand
BDBM12342
(2H-chromen-2-one | CHEMBL6466 | Coumarin)
Copy SMILES
Copy InChI
Affinity Data
Ki: 9.20E+3nM
Assay Description:
Inhibition of human carbonic anhydrase 2 preincubated for 6 hrs by CO2 hydration stopped-flow assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
KEGG
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Carbonic anhydrase 2
(Homo sapiens (Human))
Latvian Association Of Human Genetics
Curated by
ChEMBL
Ligand
BDBM12342
(2H-chromen-2-one | CHEMBL6466 | Coumarin)
Copy SMILES
Copy InChI
Affinity Data
Ki: 9.20E+3nM
Assay Description:
Inhibition of human carbonic anhydrase 2 after 6 hrs by stop-flow CO2 hydration assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
KEGG
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Carbonic anhydrase 2
(Homo sapiens (Human))
Latvian Association Of Human Genetics
Curated by
ChEMBL
Ligand
BDBM12342
(2H-chromen-2-one | CHEMBL6466 | Coumarin)
Copy SMILES
Copy InChI
Affinity Data
Ki: 9.20E+3nM
Assay Description:
Inhibition of human recombinant carbonic anhydrase 2 preincubated for 15 mins to 72 hrs measured after 6 hrs by stopped flow CO2 hydration method
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
KEGG
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Carbonic anhydrase 2
(Homo sapiens (Human))
Latvian Association Of Human Genetics
Curated by
ChEMBL
Ligand
BDBM12342
(2H-chromen-2-one | CHEMBL6466 | Coumarin)
Copy SMILES
Copy InChI
Affinity Data
Ki: 9.20E+3nM
Assay Description:
Inhibition of human full-length cytosolic CA2 after 6 hrs by stopped flow CO2 hydration assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
KEGG
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Carbonic anhydrase 2
(Homo sapiens (Human))
Latvian Association Of Human Genetics
Curated by
ChEMBL
Ligand
BDBM12342
(2H-chromen-2-one | CHEMBL6466 | Coumarin)
Copy SMILES
Copy InChI
Affinity Data
Ki: 9.20E+3nM
Assay Description:
Inhibition of human CA2 pre-incubated for 15 mins to 24 hrs measured after 6 hrs by phenol red-based stopped-flow CO2 hydrase assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
KEGG
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Carbonic anhydrase 2
(Homo sapiens (Human))
Latvian Association Of Human Genetics
Curated by
ChEMBL
Ligand
BDBM12342
(2H-chromen-2-one | CHEMBL6466 | Coumarin)
Copy SMILES
Copy InChI
Affinity Data
Ki: 9.20E+3nM
Assay Description:
Inhibition of full length human CA2 cytosolic isoform by stopped-flow CO2 hydration method
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
KEGG
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Carbonic anhydrase 2
(Homo sapiens (Human))
Latvian Association Of Human Genetics
Curated by
ChEMBL
Ligand
BDBM12342
(2H-chromen-2-one | CHEMBL6466 | Coumarin)
Copy SMILES
Copy InChI
Affinity Data
Ki: 9.20E+3nM
Assay Description:
Inhibition of human carbonic anhydrase 2 by Stopped-Flow CO2 Hydrase assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
KEGG
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Acetylcholinesterase
(Mus musculus (mouse))
Mayo Clinic
Ligand
BDBM12342
(2H-chromen-2-one | CHEMBL6466 | Coumarin)
Copy SMILES
Copy InChI
Affinity Data
Ki: 9.30E+3nM ΔG°: -28.7kJ/mole
pH: 7.0 T: 2°C
Assay Description:
Assays were conducted at 25 C in 20 mM sodium phosphate buffer (pH 7.0) and 0.01% bovine serum albumin unless otherwise noted. AChE concentrations we...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
KEGG
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Carbonic anhydrase 5A, mitochondrial
(Homo sapiens (Human))
Universita Degli Studi Di Firenze
Curated by
ChEMBL
Ligand
BDBM12342
(2H-chromen-2-one | CHEMBL6466 | Coumarin)
Copy SMILES
Copy InChI
Affinity Data
Ki: 9.40E+3nM
Assay Description:
Inhibition of human carbonic anhydrase 5A by stopped flow CO2 hydration assay
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
KEGG
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Carbonic anhydrase 15
(Mus musculus)
Universita Degli Studi Di Firenze
Curated by
ChEMBL
Ligand
BDBM12342
(2H-chromen-2-one | CHEMBL6466 | Coumarin)
Copy SMILES
Copy InChI
Affinity Data
Ki: 3.96E+4nM
Assay Description:
Inhibition of mouse carbonic anhydrase 15 by stopped flow CO2 hydration assay
More data for this Ligand-Target Pair
Target Info
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
KEGG
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Carbonic anhydrase 4
(Homo sapiens (Human))
Universita Degli Studi Di Firenze
Curated by
ChEMBL
Ligand
BDBM12342
(2H-chromen-2-one | CHEMBL6466 | Coumarin)
Copy SMILES
Copy InChI
Affinity Data
Ki: 6.23E+4nM
Assay Description:
Inhibition of human recombinant carbonic anhydrase 4 preincubated for 15 mins to 72 hrs measured after 6 hrs by stopped flow CO2 hydration method
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
KEGG
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Carbonic anhydrase 9
(Homo sapiens (Human))
Università
Curated by
ChEMBL
Ligand
BDBM12342
(2H-chromen-2-one | CHEMBL6466 | Coumarin)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+5nM
Assay Description:
Inhibition of human recombinant transmembrane CA9 catalytic domain after 6 hrs by stopped-flow CO2 hydration method
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
KEGG
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Carbonic anhydrase 12
(Homo sapiens (Human))
Universita Degli Studi Di Firenze
Curated by
ChEMBL
Ligand
BDBM12342
(2H-chromen-2-one | CHEMBL6466 | Coumarin)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+5nM
Assay Description:
Inhibition of human recombinant transmembrane CA12 catalytic domain after 6 hrs by stopped-flow CO2 hydration method
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
KEGG
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Carbonic anhydrase 9
(Homo sapiens (Human))
Università
Curated by
ChEMBL
Ligand
BDBM12342
(2H-chromen-2-one | CHEMBL6466 | Coumarin)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+5nM
Assay Description:
Inhibition of human carbonic anhydrase 9 catalytic domain by Stopped-Flow CO2 Hydrase assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
KEGG
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Carbonic anhydrase 12
(Homo sapiens (Human))
Universita Degli Studi Di Firenze
Curated by
ChEMBL
Ligand
BDBM12342
(2H-chromen-2-one | CHEMBL6466 | Coumarin)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+5nM
Assay Description:
Inhibition of human carbonic anhydrase 12 catalytic domain by Stopped-Flow CO2 Hydrase assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
KEGG
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Carbonic anhydrase 9
(Homo sapiens (Human))
Università
Curated by
ChEMBL
Ligand
BDBM12342
(2H-chromen-2-one | CHEMBL6466 | Coumarin)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+5nM
Assay Description:
Inhibition of human CA9 pre-incubated for 15 mins to 24 hrs measured after 6 hrs by phenol red-based stopped-flow CO2 hydrase assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
KEGG
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Carbonic anhydrase 12
(Homo sapiens (Human))
Universita Degli Studi Di Firenze
Curated by
ChEMBL
Ligand
BDBM12342
(2H-chromen-2-one | CHEMBL6466 | Coumarin)
Copy SMILES
Copy InChI
Affinity Data
Ki: >2.00E+5nM
Assay Description:
Inhibition of human recombinant carbonic anhydrase 12 preincubated for 15 mins to 72 hrs measured after 6 hrs by stopped flow CO2 hydration method
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
KEGG
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Carbonic anhydrase 9
(Homo sapiens (Human))
Università
Curated by
ChEMBL
Ligand
BDBM12342
(2H-chromen-2-one | CHEMBL6466 | Coumarin)
Copy SMILES
Copy InChI
Affinity Data
Ki: >2.00E+5nM
Assay Description:
Inhibition of human recombinant carbonic anhydrase 9 preincubated for 15 mins to 72 hrs measured after 6 hrs by stopped flow CO2 hydration method
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
KEGG
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Carbonic anhydrase 13
(Homo sapiens (Human))
Universit£
Curated by
ChEMBL
Ligand
BDBM12342
(2H-chromen-2-one | CHEMBL6466 | Coumarin)
Copy SMILES
Copy InChI
Affinity Data
Ki: >2.00E+5nM
Assay Description:
Inhibition of human recombinant carbonic anhydrase 13 preincubated for 15 mins to 72 hrs measured after 6 hrs by stopped flow CO2 hydration method
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
KEGG
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Carbonic anhydrase 14
(Homo sapiens (Human))
Universita Degli Studi Di Firenze
Curated by
ChEMBL
Ligand
BDBM12342
(2H-chromen-2-one | CHEMBL6466 | Coumarin)
Copy SMILES
Copy InChI
Affinity Data
Ki: >2.00E+5nM
Assay Description:
Inhibition of human recombinant carbonic anhydrase 14 preincubated for 15 mins to 72 hrs measured after 6 hrs by stopped flow CO2 hydration method
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
KEGG
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Carbonic anhydrase 12
(Homo sapiens (Human))
Universita Degli Studi Di Firenze
Curated by
ChEMBL
Ligand
BDBM12342
(2H-chromen-2-one | CHEMBL6466 | Coumarin)
Copy SMILES
Copy InChI
Affinity Data
Ki: >2.00E+5nM
Assay Description:
Inhibition of human carbonic anhydrase 12 after 6 hrs by stop-flow CO2 hydration assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
KEGG
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Carbonic anhydrase 5A, mitochondrial
(Homo sapiens (Human))
Universita Degli Studi Di Firenze
Curated by
ChEMBL
Ligand
BDBM12342
(2H-chromen-2-one | CHEMBL6466 | Coumarin)
Copy SMILES
Copy InChI
Affinity Data
Ki: >2.00E+5nM
Assay Description:
Inhibition of human recombinant carbonic anhydrase 5A preincubated for 15 mins to 72 hrs measured after 6 hrs by stopped flow CO2 hydration method
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
KEGG
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Carbonic anhydrase 3
(Homo sapiens (Human))
Universita Degli Studi Di Firenze
Curated by
ChEMBL
Ligand
BDBM12342
(2H-chromen-2-one | CHEMBL6466 | Coumarin)
Copy SMILES
Copy InChI
Affinity Data
Ki: >2.00E+5nM
Assay Description:
Inhibition of human recombinant carbonic anhydrase 3 preincubated for 15 mins to 72 hrs measured after 6 hrs by stopped flow CO2 hydration method
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
KEGG
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Carbonic anhydrase 9
(Homo sapiens (Human))
Università
Curated by
ChEMBL
Ligand
BDBM12342
(2H-chromen-2-one | CHEMBL6466 | Coumarin)
Copy SMILES
Copy InChI
Affinity Data
Ki: >2.00E+5nM
Assay Description:
Inhibition of human carbonic anhydrase 9 after 6 hrs by stop-flow CO2 hydration assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
KEGG
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Carbonic anhydrase 7
(Homo sapiens (Human))
Universita Degli Studi Di Firenze
Curated by
ChEMBL
Ligand
BDBM12342
(2H-chromen-2-one | CHEMBL6466 | Coumarin)
Copy SMILES
Copy InChI
Affinity Data
Ki: >2.00E+5nM
Assay Description:
Inhibition of human recombinant carbonic anhydrase 7 preincubated for 15 mins to 72 hrs measured after 6 hrs by stopped flow CO2 hydration method
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
KEGG
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Carbonic anhydrase 5B, mitochondrial
(Homo sapiens (Human))
Universita Degli Studi Di Firenze
Curated by
ChEMBL
Ligand
BDBM12342
(2H-chromen-2-one | CHEMBL6466 | Coumarin)
Copy SMILES
Copy InChI
Affinity Data
Ki: >2.00E+5nM
Assay Description:
Inhibition of human recombinant carbonic anhydrase 5B preincubated for 15 mins to 72 hrs measured after 6 hrs by stopped flow CO2 hydration method
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
KEGG
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Carbonic anhydrase 6
(Homo sapiens (Human))
Universita Degli Studi Di Firenze
Curated by
ChEMBL
Ligand
BDBM12342
(2H-chromen-2-one | CHEMBL6466 | Coumarin)
Copy SMILES
Copy InChI
Affinity Data
Ki: >2.00E+5nM
Assay Description:
Inhibition of human recombinant carbonic anhydrase 6 preincubated for 15 mins to 72 hrs measured after 6 hrs by stopped flow CO2 hydration method
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
KEGG
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Carbonic anhydrase 12
(Homo sapiens (Human))
Universita Degli Studi Di Firenze
Curated by
ChEMBL
Ligand
BDBM12342
(2H-chromen-2-one | CHEMBL6466 | Coumarin)
Copy SMILES
Copy InChI
Affinity Data
Ki: >5.00E+5nM
Assay Description:
Inhibition of human recombinant CA12 after 6 hrs by stopped flow CO2 hydration assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
KEGG
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Carbonic anhydrase 9
(Homo sapiens (Human))
Università
Curated by
ChEMBL
Ligand
BDBM12342
(2H-chromen-2-one | CHEMBL6466 | Coumarin)
Copy SMILES
Copy InChI
Affinity Data
Ki: >5.00E+5nM
Assay Description:
Inhibition of human recombinant CA9 after 6 hrs by stopped flow CO2 hydration assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
KEGG
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Carbonic anhydrase 2
(Homo sapiens (Human))
Latvian Association Of Human Genetics
Curated by
ChEMBL
Ligand
BDBM12342
(2H-chromen-2-one | CHEMBL6466 | Coumarin)
Copy SMILES
Copy InChI
Affinity Data
Ki: >5.00E+5nM
Assay Description:
Inhibition of human carbonic anhydrase 2 by stopped flow CO2 hydration assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
KEGG
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Carbonic anhydrase 7
(Homo sapiens (Human))
Universita Degli Studi Di Firenze
Curated by
ChEMBL
Ligand
BDBM12342
(2H-chromen-2-one | CHEMBL6466 | Coumarin)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+6nM
Assay Description:
Inhibition of human carbonic anhydrase 7 preincubated for 6 hrs by CO2 hydration stopped-flow assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
KEGG
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Carbonic anhydrase 13
(Homo sapiens (Human))
Universit£
Curated by
ChEMBL
Ligand
BDBM12342
(2H-chromen-2-one | CHEMBL6466 | Coumarin)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+6nM
Assay Description:
Inhibition of human carbonic anhydrase 13 preincubated for 6 hrs by CO2 hydration stopped-flow assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
KEGG
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Carbonic anhydrase 12
(Homo sapiens (Human))
Universita Degli Studi Di Firenze
Curated by
ChEMBL
Ligand
BDBM12342
(2H-chromen-2-one | CHEMBL6466 | Coumarin)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+6nM
Assay Description:
Inhibition of human carbonic anhydrase 12 preincubated for 6 hrs by CO2 hydration stopped-flow assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
KEGG
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Carbonic anhydrase 9
(Homo sapiens (Human))
Università
Curated by
ChEMBL
Ligand
BDBM12342
(2H-chromen-2-one | CHEMBL6466 | Coumarin)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+6nM
Assay Description:
Inhibition of human carbonic anhydrase 9 preincubated for 6 hrs by CO2 hydration stopped-flow assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
KEGG
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Amine oxidase [flavin-containing] B
(Rattus norvegicus (rat))
Universit£
Curated by
ChEMBL
Ligand
BDBM12342
(2H-chromen-2-one | CHEMBL6466 | Coumarin)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.20E+4nM
Assay Description:
Inhibitory effect on Monoamine oxidase B, SD on IC50 values < 10%
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
KEGG
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Induced myeloid leukemia cell differentiation protein Mcl-1
(Homo sapiens (Human))
Dalian University Of Technology
Curated by
ChEMBL
Ligand
BDBM12342
(2H-chromen-2-one | CHEMBL6466 | Coumarin)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2.44E+4nM
Assay Description:
Displacement of FAM-Bid peptide from recombinant N-terminal His6x-tagged human Mcl-1 expressed in Escherichia coli BL21 (DE3) incubated for 30 mins b...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
KEGG
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Exportin-1
(Homo sapiens (Human))
Osaka University
Curated by
ChEMBL
Ligand
BDBM12342
(2H-chromen-2-one | CHEMBL6466 | Coumarin)
Copy SMILES
Copy InChI
Affinity Data
IC50: >2.50E+4nM
Assay Description:
Inhibition of CRM1-mediated hemagglutinin-tagged HIV1 Rev protein nuclear export in human HeLa cells assessed as nucleus localization after 12 hrs by...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
KEGG
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Amine oxidase [flavin-containing] A
(Rattus norvegicus (rat))
Universit£
Curated by
ChEMBL
Ligand
BDBM12342
(2H-chromen-2-one | CHEMBL6466 | Coumarin)
Copy SMILES
Copy InChI
Affinity Data
IC50: 4.07E+4nM
Assay Description:
Inhibitory effect on monoamine oxidase A, SD on IC50 values < 10%
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
KEGG
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
UDP-glucuronosyltransferase 2B10
(Homo sapiens (Human))
Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences
Ligand
BDBM12342
(2H-chromen-2-one | CHEMBL6466 | Coumarin)
Copy SMILES
Copy InChI
Affinity Data
IC50: >3.00E+5nM
Assay Description:
Refer to Fisher et al., Drug Metab. Dispos., 28:560-566.
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
KEGG
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
UDP-glucuronosyltransferase 2B7
(Homo sapiens (Human))
Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences
Ligand
BDBM12342
(2H-chromen-2-one | CHEMBL6466 | Coumarin)
Copy SMILES
Copy InChI
Affinity Data
IC50: >3.00E+5nM
Assay Description:
Refer to Fisher et al., Drug Metab. Dispos., 28:560-566.
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
KEGG
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
UDP-glucuronosyltransferase 1-6
(Homo sapiens (Human))
Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences
Ligand
BDBM12342
(2H-chromen-2-one | CHEMBL6466 | Coumarin)
Copy SMILES
Copy InChI
Affinity Data
IC50: >3.00E+5nM
Assay Description:
Refer to Fisher et al., Drug Metab. Dispos., 28:560-566.
More data for this Ligand-Target Pair
Target Info
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
KEGG
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
UDP-glucuronosyltransferase 1A1
(Homo sapiens (Human))
Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences
Ligand
BDBM12342
(2H-chromen-2-one | CHEMBL6466 | Coumarin)
Copy SMILES
Copy InChI
Affinity Data
IC50: >3.00E+5nM
Assay Description:
Refer to Fisher et al., Drug Metab. Dispos., 28:560-566.
More data for this Ligand-Target Pair
Target Info
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
KEGG
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
UDP-glucuronosyltransferase 1A4
(Homo sapiens (Human))
Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences
Ligand
BDBM12342
(2H-chromen-2-one | CHEMBL6466 | Coumarin)
Copy SMILES
Copy InChI
Affinity Data
IC50: >3.00E+5nM
Assay Description:
Refer to Fisher et al., Drug Metab. Dispos., 28:560-566.
More data for this Ligand-Target Pair
Target Info
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
KEGG
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Sorbitol dehydrogenase
(Homo sapiens (Human))
University Of Toyama
Curated by
ChEMBL
Ligand
BDBM12342
(2H-chromen-2-one | CHEMBL6466 | Coumarin)
Copy SMILES
Copy InChI
Affinity Data
IC50: >4.00E+5nM
Assay Description:
Inhibition sorbitol dehydrogenase by spectrophotometric analysis
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
KEGG
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Aldo-keto reductase family 1 member B1
(Homo sapiens (Human))
University Of Toyama
Curated by
ChEMBL
Ligand
BDBM12342
(2H-chromen-2-one | CHEMBL6466 | Coumarin)
Copy SMILES
Copy InChI
Affinity Data
IC50: >5.00E+5nM
Assay Description:
Inhibition human recombinant aldose reductase 1 by spectrophotometric analysis
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
KEGG
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Beta-secretase 1
(Homo sapiens (Human))
Kinki University
Curated by
ChEMBL
Ligand
BDBM12342
(2H-chromen-2-one | CHEMBL6466 | Coumarin)
Copy SMILES
Copy InChI
Affinity Data
IC50: >5.00E+5nM
Assay Description:
Inhibition of recombinant human BACE1 using Rh-EVNLDAEFK as substrate after 60 mins by fluorescence quenching assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
KEGG
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Dihydroorotate dehydrogenase (fumarate)
(Leishmania major)
University Of S£O Paulo
Curated by
ChEMBL
Ligand
BDBM12342
(2H-chromen-2-one | CHEMBL6466 | Coumarin)
Copy SMILES
Copy InChI
Affinity Data
IC50: 6.31E+5nM
Assay Description:
Inhibition of recombinant oligo-histidine-tagged Leishmania major DHODH expressed in Escherichia coli BL21(DE3) cells using DHO as substrate measured...
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
KEGG
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Dihydroorotate dehydrogenase (fumarate)
(Leishmania major)
University Of S£O Paulo
Curated by
ChEMBL
Ligand
BDBM12342
(2H-chromen-2-one | CHEMBL6466 | Coumarin)
Copy SMILES
Copy InChI
Affinity Data
IC50: 6.42E+5nM
Assay Description:
Inhibition of recombinant oligo-histidine-tagged Leishmania major DHODH expressed in Escherichia coli BL21(DE3) cells using DHO as substrate measured...
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
KEGG
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Glyceraldehyde-3-phosphate dehydrogenase, glycosomal
(Trypanosoma cruzi)
Universidade De S£O Paulo
Curated by
ChEMBL
Ligand
BDBM12342
(2H-chromen-2-one | CHEMBL6466 | Coumarin)
Copy SMILES
Copy InChI
Affinity Data
IC50: 6.92E+5nM
Assay Description:
Inhibition of Trypanosoma cruzi recombinant glycosomal GAPDH expressed in Escherichia coli by spectrophotometry
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
KEGG
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Glyceraldehyde-3-phosphate dehydrogenase
(Homo sapiens (Human))
Universidade Federal De Minas Gerais
Curated by
ChEMBL
Ligand
BDBM12342
(2H-chromen-2-one | CHEMBL6466 | Coumarin)
Copy SMILES
Copy InChI
Affinity Data
IC50: 6.92E+5nM
Assay Description:
Inhibitory concentration against glyceraldehyde-3-phosphate dehydrogenase was determined as log 1/IC50
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
KEGG
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Bile salt export pump
(Homo sapiens (Human))
Astrazeneca
Curated by
ChEMBL
Ligand
BDBM12342
(2H-chromen-2-one | CHEMBL6466 | Coumarin)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+6nM
Assay Description:
Inhibition of human skin fibroblast Collagenase at pH 7.5
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
KEGG
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Displayed 1 to 50 (of 73 total ) |
Next
|
Last
>>