Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetBeta-adrenergic receptor kinase 1(Homo sapiens (Human))
Janssen Research & Development

Curated by ChEMBL

LigandBDBM50554263(CHEMBL4740635)Copy SMILESCopy InChI

Affinity DataIC50:  95nMAssay Description:Inhibition of human GRK2 by transcreener assayMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sidPDB

In DepthDetails ArticlePubMedPDB3D Structure (crystal)
Copy BDB DOI

TargetG protein-coupled receptor kinase 5(Homo sapiens (Human))
Janssen Research & Development

Curated by ChEMBL

LigandBDBM50554263(CHEMBL4740635)Copy SMILESCopy InChI

Affinity DataKd:  3.43E+4nMAssay Description:Binding affinity to GRK5 (unknown origin) by Thermofluor thermal shift assayMore data for this Ligand-Target Pair

Target InfoPDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoPC cidPC sidPDB

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetRhodopsin kinase GRK1(Homo sapiens (Human))
Janssen Research & Development

Curated by ChEMBL

LigandBDBM50554263(CHEMBL4740635)Copy SMILESCopy InChI

Affinity DataKd:  1.45E+4nMAssay Description:Binding affinity to GRK1 (unknown origin) by Thermofluor thermal shift assayMore data for this Ligand-Target Pair

Target InfoPDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoPC cidPC sidPDB

In DepthDetails ArticlePubMed
Copy BDB DOI