Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetCeramide glucosyltransferase(Homo sapiens (Human))
TBA

US Patent

LigandBDBM367620(N-((1R,2R)-3-(azetidin-1-yl)-1-(3- chloro-4-cyclop...)Copy SMILESCopy InChI

Affinity DataIC50:  55nMAssay Description:Protein concentration was determined using BCA assay kit. Sixty micrograms of MDCK cell lysate was incubated with various concentrations of a compoun...More data for this Ligand-Target Pair

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Ligand InfoPC cidPC sid

In DepthDetails US Patent
Copy BDB DOI

TargetCeramide glucosyltransferase(Homo sapiens (Human))
TBA

US Patent

LigandBDBM367620(N-((1R,2R)-3-(azetidin-1-yl)-1-(3- chloro-4-cyclop...)Copy SMILESCopy InChI

Affinity DataIC50:  55nMAssay Description:This assay was modified based on the study by Larsen et al. (J. Lipid Res. 2011, 53, 282). Madin-Darby canine kidney (MDCK) cell lysate was prepared ...More data for this Ligand-Target Pair

Target InfoNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails US Patent
Copy BDB DOI