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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
6
hits in this display
Target
Beta-2 adrenergic receptor
(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by
ChEMBL
Ligand
BDBM50324856
(7-((R)-2-((cis)-bi(cyclopentan)-2-ylamino)-1-hydro...)
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Affinity Data
Ki: 0.600nM
Assay Description:
Displacement of [3H]CGP12177 from human beta2 adrenoceptor
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Beta-2 adrenergic receptor
(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by
ChEMBL
Ligand
BDBM50324856
(7-((R)-2-((cis)-bi(cyclopentan)-2-ylamino)-1-hydro...)
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Copy InChI
Affinity Data
Ki: 0.800nM
Assay Description:
Displacement of [125I]iodo-(+/-)-cyanopindolol from human adrenergic beta2 receptor expressed in CHO cells after 3 hrs by radio-ligand binding assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Beta-1 adrenergic receptor
(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by
ChEMBL
Ligand
BDBM50324856
(7-((R)-2-((cis)-bi(cyclopentan)-2-ylamino)-1-hydro...)
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Copy InChI
Affinity Data
Ki: 17nM
Assay Description:
Displacement of [125I]iodo-(+/-)-cyanopindolol from human adrenergic beta1 receptor expressed in CHO cells after 3 hrs by radio-ligand binding assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Beta-1 adrenergic receptor
(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by
ChEMBL
Ligand
BDBM50324856
(7-((R)-2-((cis)-bi(cyclopentan)-2-ylamino)-1-hydro...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 18nM
Assay Description:
Displacement of [3H]CGP12177 from human beta-1 adrenoceptor
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(3) dopamine receptor
(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by
ChEMBL
Ligand
BDBM50324856
(7-((R)-2-((cis)-bi(cyclopentan)-2-ylamino)-1-hydro...)
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Copy InChI
Affinity Data
Ki: 842nM
Assay Description:
Displacement of [125I]7-HO-PIPAT from human D3R expressed in HEK cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Beta-2 adrenergic receptor
(GUINEA PIG)
Novartis Institutes For Biomedical Research
Curated by
ChEMBL
Ligand
BDBM50324856
(7-((R)-2-((cis)-bi(cyclopentan)-2-ylamino)-1-hydro...)
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Copy InChI
Affinity Data
IC50: 0.300nM
Assay Description:
Agonist activity at adrenergic beta2 receptor in electrically-stimulated Dunkin-Hartley guinea pig tracheal strip assessed as inhibition of contracti...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI