Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetBeta-1 adrenergic receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL

LigandBDBM50418946(CHEMBL1807817)Copy SMILESCopy InChI

Affinity DataIC50:  7.90nMAssay Description:Binding affinity to adrenergic beta1 receptorMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetD(2) dopamine receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL

LigandBDBM50418946(CHEMBL1807817)Copy SMILESCopy InChI

Affinity DataIC50: <1.00E+3nMAssay Description:Binding affinity to dopamine 2 receptorMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL

LigandBDBM50418946(CHEMBL1807817)Copy SMILESCopy InChI

Affinity DataEC50:  0.0631nMAssay Description:Agonist activity at human adrenergic beta2 receptor expressed in H292 cells assessed as stimulation of cAMP accumulation after 60 minsMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI