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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
14
hits in this display
Target
Beta-1 adrenergic receptor
(Homo sapiens (Human))
Merck Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50070132
((S)-N-(4-(2-(2-hydroxy-3-(4-hydroxyphenoxy)propyla...)
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Affinity Data
IC50: 180nM
Assay Description:
Tested for binding affinity against cloned human beta-1 adrenergic receptor from CHO cells using [125I]-iodocyanopindolol as the radioligand
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Beta-2 adrenergic receptor
(Homo sapiens (Human))
Merck Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50070132
((S)-N-(4-(2-(2-hydroxy-3-(4-hydroxyphenoxy)propyla...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 190nM
Assay Description:
Binding affinity against cloned human beta-2 adrenergic receptor from CHO cells using [125I]-iodocyanopindolol as the radioligand
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Beta-3 adrenergic receptor
(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute
Curated by
ChEMBL
Ligand
BDBM50070132
((S)-N-(4-(2-(2-hydroxy-3-(4-hydroxyphenoxy)propyla...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 6.30nM
Assay Description:
Binding affinity of the compound towards human Beta-3 adrenergic receptor
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Beta-2 adrenergic receptor
(Homo sapiens (Human))
Merck Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50070132
((S)-N-(4-(2-(2-hydroxy-3-(4-hydroxyphenoxy)propyla...)
Copy SMILES
Copy InChI
Affinity Data
EC50: >1.00E+5nM
Assay Description:
Agonist activity at human cloned adrenergic beta2 receptor expressed in CHO cells assessed as increase in cAMP production after 2 days by radioimmuno...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Beta-1 adrenergic receptor
(Homo sapiens (Human))
Merck Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50070132
((S)-N-(4-(2-(2-hydroxy-3-(4-hydroxyphenoxy)propyla...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 1.60E+3nM
Assay Description:
Agonist activity at human cloned adrenergic beta-1 receptor expressed in CHO cells assessed as [125I]cAMP accumulation after 2 days by radioimmunoass...
Checked by Author
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Beta-3 adrenergic receptor
(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute
Curated by
ChEMBL
Ligand
BDBM50070132
((S)-N-(4-(2-(2-hydroxy-3-(4-hydroxyphenoxy)propyla...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 78nM
Assay Description:
Agonist activity at human cloned adrenergic beta3 receptor expressed in CHO cells assessed as increase in cAMP production after 2 days by radioimmuno...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Beta-1 adrenergic receptor
(Homo sapiens (Human))
Merck Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50070132
((S)-N-(4-(2-(2-hydroxy-3-(4-hydroxyphenoxy)propyla...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 210nM
Assay Description:
Agonist activity at human cloned adrenergic beta-1 receptor expressed in CHO cells assessed as [125I]cAMP accumulation after 2 days by radioimmunoass...
Checked by Author
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Beta-3 adrenergic receptor
(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute
Curated by
ChEMBL
Ligand
BDBM50070132
((S)-N-(4-(2-(2-hydroxy-3-(4-hydroxyphenoxy)propyla...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 78nM
Assay Description:
Agonist activity at human cloned adrenergic beta3 receptor expressed in CHO cells assessed as [125I]cAMP accumulation after 2 days by radioimmunoassa...
Checked by Author
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Beta-3 adrenergic receptor
(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute
Curated by
ChEMBL
Ligand
BDBM50070132
((S)-N-(4-(2-(2-hydroxy-3-(4-hydroxyphenoxy)propyla...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 730nM
Assay Description:
Agonist activity at human cloned adrenergic beta3 receptor expressed in CHO cells assessed as [125I]cAMP accumulation after 2 days by radioimmunoassa...
Checked by Author
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Beta-2 adrenergic receptor
(Homo sapiens (Human))
Merck Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50070132
((S)-N-(4-(2-(2-hydroxy-3-(4-hydroxyphenoxy)propyla...)
Copy SMILES
Copy InChI
Affinity Data
EC50: >1.00E+5nM
Assay Description:
Agonist activity at human cloned adrenergic beta2 receptor expressed in CHO cells assessed as [125I]cAMP accumulation after 2 days by radioimmunoassa...
Checked by Author
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Beta-2 adrenergic receptor
(Homo sapiens (Human))
Merck Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50070132
((S)-N-(4-(2-(2-hydroxy-3-(4-hydroxyphenoxy)propyla...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 20nM
Assay Description:
Agonist activity at human cloned adrenergic beta2 receptor expressed in CHO cells assessed as [125I]cAMP accumulation after 2 days by radioimmunoassa...
Checked by Author
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Beta-3 adrenergic receptor
(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute
Curated by
ChEMBL
Ligand
BDBM50070132
((S)-N-(4-(2-(2-hydroxy-3-(4-hydroxyphenoxy)propyla...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 6.30nM
Assay Description:
Agonist activity towards human Beta-3 adrenergic receptor
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Beta-3 adrenergic receptor
(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute
Curated by
ChEMBL
Ligand
BDBM50070132
((S)-N-(4-(2-(2-hydroxy-3-(4-hydroxyphenoxy)propyla...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 6.30nM
Assay Description:
Agonist activity against cloned human beta-3 adrenergic receptor
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Beta-1 adrenergic receptor
(Homo sapiens (Human))
Merck Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50070132
((S)-N-(4-(2-(2-hydroxy-3-(4-hydroxyphenoxy)propyla...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 1.60E+3nM
Assay Description:
Agonist activity at human cloned adrenergic beta-1 receptor expressed in CHO cells assessed as increase in cAMP production after 2 days by radioimmun...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI