Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetProlyl endopeptidase(Homo sapiens (Human))
Genentech

Curated by ChEMBL

LigandBDBM50200728((R)-1-(4-oxo-4-phenylbutanoyl)pyrrolidin-2-ylboron...)Copy SMILESCopy InChI

Affinity DataKi:  1.70nMAssay Description:Inhibitory constant against POPMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetProlyl endopeptidase FAP(Homo sapiens (Human))
Genentech

Curated by ChEMBL

LigandBDBM50200728((R)-1-(4-oxo-4-phenylbutanoyl)pyrrolidin-2-ylboron...)Copy SMILESCopy InChI

Affinity DataKi:  94nMAssay Description:Inhibitiory constant against FAPMore data for this Ligand-Target Pair

Target InfoPDBMMDBKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Genentech

Curated by ChEMBL

LigandBDBM50200728((R)-1-(4-oxo-4-phenylbutanoyl)pyrrolidin-2-ylboron...)Copy SMILESCopy InChI

Affinity DataKi:  4.51E+5nMAssay Description:Inhibition constant against DPP-4More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI