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Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
10
hits in this display
Target
Prolyl endopeptidase
(Homo sapiens (Human))
Genentech
Curated by
ChEMBL
Ligand
BDBM50200723
((R)-1-(2-(1-oxoisoindolin-2-yl)acetyl)pyrrolidin-2...)
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Affinity Data
Ki: 2.80nM
Assay Description:
Inhibitory constant against POP
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Prolyl endopeptidase FAP
(Homo sapiens (Human))
Genentech
Curated by
ChEMBL
Ligand
BDBM50200723
((R)-1-(2-(1-oxoisoindolin-2-yl)acetyl)pyrrolidin-2...)
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Affinity Data
Ki: 7.5nM
Assay Description:
Inhibitiory constant against FAP
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Dipeptidyl peptidase 4
(Homo sapiens (Human))
Genentech
Curated by
ChEMBL
Ligand
BDBM50200723
((R)-1-(2-(1-oxoisoindolin-2-yl)acetyl)pyrrolidin-2...)
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Affinity Data
Ki: 2.27E+4nM
Assay Description:
Inhibition constant against DPP-4
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Prolyl endopeptidase
(Homo sapiens (Human))
Genentech
Curated by
ChEMBL
Ligand
BDBM50200723
((R)-1-(2-(1-oxoisoindolin-2-yl)acetyl)pyrrolidin-2...)
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Affinity Data
IC50: 7.20nM
Assay Description:
Inhibition of human PREP using Z-Gly-Pro-AMC as substrate preincubated for 10 mins prior to substrate addition by fluorescence assay
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Prolyl endopeptidase FAP
(Homo sapiens (Human))
Genentech
Curated by
ChEMBL
Ligand
BDBM50200723
((R)-1-(2-(1-oxoisoindolin-2-yl)acetyl)pyrrolidin-2...)
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Copy InChI
Affinity Data
IC50: 93nM
Assay Description:
Inhibition of human FAP using Z-Gly-Pro-AMC as substrate preincubated for 10 mins prior to substrate addition by fluorescence assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Prolyl endopeptidase FAP
(Homo sapiens (Human))
Genentech
Curated by
ChEMBL
Ligand
BDBM50200723
((R)-1-(2-(1-oxoisoindolin-2-yl)acetyl)pyrrolidin-2...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 120nM
Assay Description:
Inhibition of human recombinant FAP expressed in Hi5 insect cells
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Dipeptidyl peptidase 9
(Homo sapiens (Human))
National Health Research Institutes
Curated by
ChEMBL
Ligand
BDBM50200723
((R)-1-(2-(1-oxoisoindolin-2-yl)acetyl)pyrrolidin-2...)
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Affinity Data
IC50: 6.50E+3nM
Assay Description:
Inhibition of human recombinant His-tagged DPP9 expressed in insect cells
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Dipeptidyl peptidase 4
(Homo sapiens (Human))
Genentech
Curated by
ChEMBL
Ligand
BDBM50200723
((R)-1-(2-(1-oxoisoindolin-2-yl)acetyl)pyrrolidin-2...)
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Affinity Data
IC50: 8.00E+3nM
Assay Description:
Inhibition of human recombinant His-tagged DPP4 expressed in insect cells
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Dipeptidyl peptidase 8
(Homo sapiens (Human))
National Health Research Institutes
Curated by
ChEMBL
Ligand
BDBM50200723
((R)-1-(2-(1-oxoisoindolin-2-yl)acetyl)pyrrolidin-2...)
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Affinity Data
IC50: 1.10E+4nM
Assay Description:
Inhibition of human recombinant His-tagged DPP8 expressed in insect cells
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Dipeptidyl peptidase 2
(Homo sapiens (Human))
National Health Research Institutes
Curated by
ChEMBL
Ligand
BDBM50200723
((R)-1-(2-(1-oxoisoindolin-2-yl)acetyl)pyrrolidin-2...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+5nM
Assay Description:
Inhibition of human recombinant His-tagged DPP2 expressed in insect cells
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI