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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 7 hits in this display   

TargetTYR_PHOSPHATASE_2 domain-containing protein(Mycobacterium tuberculosis)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50167965(CHEMBL3248231 | US11192850, Compound 1)
Affinity DataIC50:  5.40E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis PTPB expressed in Escherichia coli BL21 (DE3) using p-nitrophenyl phosphate as substrate measured after 30 m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTriple specificity protein phosphatase PtpB()
Purdue Research Foundation

US Patent
LigandPNGBDBM50167965(CHEMBL3248231 | US11192850, Compound 1)
Affinity DataIC50:  5.40E+3nMAssay Description:Compounds were tested against mPTPB using the p-nitrophenyl phosphate (pNPP) assay system in a Cary 100 UV-Vis spectrophotometer by monitoring the in...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
Purdue Research Foundation

US Patent
LigandPNGBDBM50167965(CHEMBL3248231 | US11192850, Compound 1)
Affinity DataIC50: >1.00E+5nMAssay Description:Compounds were tested against mPTPB using the p-nitrophenyl phosphate (pNPP) assay system in a Cary 100 UV-Vis spectrophotometer by monitoring the in...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50167965(CHEMBL3248231 | US11192850, Compound 1)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of PTP1B (unknown origin) expressed in Escherichia coli BL21 using p-nitrophenyl phosphate as substrate measured after 30 mins by UV-vis s...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
Purdue Research Foundation

US Patent
LigandPNGBDBM50167965(CHEMBL3248231 | US11192850, Compound 1)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of SHP2 (unknown origin) expressed in Escherichia coli BL21 using p-nitrophenyl phosphate as substrate measured after 30 mins by UV-vis sp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50167965(CHEMBL3248231 | US11192850, Compound 1)
Affinity DataIC50: >1.00E+5nMAssay Description:Compounds were tested against mPTPB using the p-nitrophenyl phosphate (pNPP) assay system in a Cary 100 UV-Vis spectrophotometer by monitoring the in...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetC-terminal-binding protein 2(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50167965(CHEMBL3248231 | US11192850, Compound 1)
Affinity DataIC50: >3.00E+5nMAssay Description:Inhibition of recombinant His6-tagged CtBP2 (31 to 384 residues) (unknown origin) dehydrogenase activity expressed in Escherichia coli BL21-Codonplus...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed