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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
7
hits in this display
Target
Peroxisome proliferator-activated receptor alpha
(Homo sapiens (Human))
Bayer Healthcare Pharmaceuticals
Ligand
BDBM21753
(2-[(1S)-5-(3-phenoxypropoxy)-2,3-dihydro-1H-inden-...)
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Affinity Data
EC50: >1.00E+4nM
pH: 7.4 T: 2°C
Assay Description:
Activity was assessed by measuring the human PPAR ligand binding domain with the co-activator protein. Europium labeled anti-GST antibody, streptavid...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Peroxisome proliferator-activated receptor delta
(Homo sapiens (Human))
Bayer Healthcare Pharmaceuticals
Ligand
BDBM21753
(2-[(1S)-5-(3-phenoxypropoxy)-2,3-dihydro-1H-inden-...)
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Affinity Data
EC50: 44nM
T: 2°C
Assay Description:
Activity was assessed by measuring the human PPAR ligand binding domain with the co-activator protein. Europium labeled anti-GST antibody, streptavid...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human))
Bayer Healthcare Pharmaceuticals
Ligand
BDBM21753
(2-[(1S)-5-(3-phenoxypropoxy)-2,3-dihydro-1H-inden-...)
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Copy InChI
Affinity Data
EC50: >1.00E+4nM
T: 2°C
Assay Description:
PPAR gamma activity was assessed by using the IRBA in mouse 3T3-L1 cells. This assay measures the ability of test compound to cause an increase in th...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Peroxisome proliferator-activated receptor alpha
(Homo sapiens (Human))
Bayer Healthcare Pharmaceuticals
Ligand
BDBM21753
(2-[(1S)-5-(3-phenoxypropoxy)-2,3-dihydro-1H-inden-...)
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Copy InChI
Affinity Data
EC50: >1.00E+4nM
Assay Description:
Agonist activity at human GAL4 fused PPARalpha-LBD expressed in human HepG2 cells after 18 hrs by luciferase reporter gene assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human))
Bayer Healthcare Pharmaceuticals
Ligand
BDBM21753
(2-[(1S)-5-(3-phenoxypropoxy)-2,3-dihydro-1H-inden-...)
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Copy InChI
Affinity Data
EC50: >1.00E+4nM
Assay Description:
Agonist activity at human GAL4 fused PPARgamma-LBD expressed in HEK293 cells after 18 hrs by luciferase reporter gene assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Free fatty acid receptor 1
(Homo sapiens (Human))
Guangdong Pharmaceutical University
Curated by
ChEMBL
Ligand
BDBM21753
(2-[(1S)-5-(3-phenoxypropoxy)-2,3-dihydro-1H-inden-...)
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Affinity Data
EC50: >1.00E+4nM
Assay Description:
Agonist activity at human FFA1 expressed in CHO cells assessed as increase in intracellular Ca2+ flux after 1 hr by Fluo4-AM dye based FLIPR assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Peroxisome proliferator-activated receptor delta
(Homo sapiens (Human))
Bayer Healthcare Pharmaceuticals
Ligand
BDBM21753
(2-[(1S)-5-(3-phenoxypropoxy)-2,3-dihydro-1H-inden-...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 170nM
Assay Description:
Agonist activity at human GAL4 fused PPARdelta-LBD expressed in HEK293 cells after 18 hrs by luciferase reporter gene assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI