Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)
Found 4 hits in this display
Caspase-8(Homo sapiens (Human))Histogen
US Patent
BDBM572147(US11447497, Example 4)
Caspase-1(Homo sapiens (Human))Histogen
US Patent
BDBM572147(US11447497, Example 4)
IC50: 2nMAssay Description:Caspase-1 was diluted to 10 U/μl in assay buffer consisting of 50 mM HEPES, pH 7.4, 100 mM NaCl, 0.1% CHAPS, 1 mM EDTA, 10% glycerol and 10 mM D...More data for this Ligand-Target Pair
Caspase-9(Homo sapiens (Human))Histogen
US Patent
BDBM572147(US11447497, Example 4)
IC50: 107nMAssay Description:Caspase-1 was diluted to 10 U/μl in assay buffer consisting of 50 mM HEPES, pH 7.4, 100 mM NaCl, 0.1% CHAPS, 1 mM EDTA, 10% glycerol and 10 mM D...More data for this Ligand-Target Pair
Caspase-3(Homo sapiens (Human))Histogen
US Patent
BDBM572147(US11447497, Example 4)
IC50: 200nMAssay Description:Caspase-1 was diluted to 10 U/μl in assay buffer consisting of 50 mM HEPES, pH 7.4, 100 mM NaCl, 0.1% CHAPS, 1 mM EDTA, 10% glycerol and 10 mM D...More data for this Ligand-Target Pair