Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetCysteinyl leukotriene receptor 2(Homo sapiens (Human))
Ono Pharmaceutical

Curated by ChEMBL

LigandBDBM50066909(CHEMBL3401688)Copy SMILESCopy InChI

Affinity DataIC50:  16nMAssay Description:Antagonist activity at human CysLT2 receptor expressed in HEK293 cells assessed as inhibition of LTD4-inudced intracellular calcium influx preincubat...More data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetCysteinyl leukotriene receptor 1(Homo sapiens (Human))
Ono Pharmaceutical

Curated by ChEMBL

LigandBDBM50066909(CHEMBL3401688)Copy SMILESCopy InChI

Affinity DataIC50:  82nMAssay Description:Antagonist activity at human CysLT2 receptor expressed in HEK293 cells assessed as inhibition of LTD4-inudced intracellular calcium influx preincubat...More data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI