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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
4
hits in this display
Target
Peroxisome proliferator-activated receptor delta
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50212708
(2-(7-(4-(4-(trifluoromethyl)benzyloxy)benzylthio)-...)
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Affinity Data
IC50: 10nM
Assay Description:
Displacement of [3H]2-(4-(3-(4-acetyl-3-hydroxy-2 propyl-phenoxy)propoxy)phenoxy)acetic acid from human PPARdelta after 30 mins by SPA assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
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Target
Peroxisome proliferator-activated receptor alpha
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50212708
(2-(7-(4-(4-(trifluoromethyl)benzyloxy)benzylthio)-...)
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Copy InChI
Affinity Data
IC50: 1.20E+3nM
Assay Description:
Displacement of [3H]2-(4-(2-(3-(2,4-difluorophenyl)-1-heptylureido)ethyl)phenoxy)-2-methylbutanoic acid from human PPARalpha after 30 mins by SPA ass...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50212708
(2-(7-(4-(4-(trifluoromethyl)benzyloxy)benzylthio)-...)
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Copy InChI
Affinity Data
IC50: >1.00E+4nM
Assay Description:
Displacement of [3H]5-(4-(3-(5-methyl-2-phenyloxazol-4-yl)propanoyl)benzyl)thiazolidine-2,4-dione from human PPARgamma after 2 hrs by SPA assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Peroxisome proliferator-activated receptor delta
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50212708
(2-(7-(4-(4-(trifluoromethyl)benzyloxy)benzylthio)-...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 251nM
Assay Description:
Agonist activity at human PPARdelta expressed in HepG2 cells after 16 hrs by luciferase reporter gene assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI