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Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
3
hits in this display
Target
Polyunsaturated fatty acid 5-lipoxygenase
(Homo sapiens (Human))
Abbott Laboratories
Curated by
ChEMBL
Ligand
BDBM50085160
(CHEMBL32842 | L-674636 | {4-(4-Chloro-phenyl)-1-[4...)
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Affinity Data
IC50: 7nM
Assay Description:
Inhibition of calcium ionophore (A-23187)-stimulated LTB4 formation in human neutrophil assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
CHEMBL
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Article
PubMed
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Target
Polyunsaturated fatty acid 5-lipoxygenase
(Rattus norvegicus)
TBA
Ligand
BDBM50085160
(CHEMBL32842 | L-674636 | {4-(4-Chloro-phenyl)-1-[4...)
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Affinity Data
IC50: 20nM
Assay Description:
Inhibition of 5-LOX in indomethacin stimulated rat PMNL cells assessed as reduction in 5-LO product level incubated for 3 mins by scintillation count...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
PubMed
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Target
Arachidonate 5-lipoxygenase-activating protein
(Homo sapiens (Human))
TBA
Curated by
ChEMBL
Ligand
BDBM50085160
(CHEMBL32842 | L-674636 | {4-(4-Chloro-phenyl)-1-[4...)
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Affinity Data
IC50: 122nM
Assay Description:
The compound was tested for the inhibition of binding of [125I]- L- 691,831 binding to 5-lipoxygenase activating protein (FLAP)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
Copy BDB DOI