Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Universitat De Barcelona

Curated by ChEMBL

LigandBDBM50213559(2-(N-(2-Ffuorophenyl)pyrrol-3-yl) acetic acid | CH...)Copy SMILESCopy InChI

Affinity DataIC50:  2.40E+3nMAssay Description:Inhibition of COX2 in human whole blood after 15 minsMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sid

In DepthDetails ArticlePubMed
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TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Universitat De Barcelona

Curated by ChEMBL

LigandBDBM50213559(2-(N-(2-Ffuorophenyl)pyrrol-3-yl) acetic acid | CH...)Copy SMILESCopy InChI

Affinity DataIC50:  1.06E+4nMAssay Description:Inhibition of COX1 in human whole blood after 15 minsMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetDehydrogenase/reductase SDR family member 9(Rattus norvegicus)
Universitat De Barcelona

Curated by ChEMBL

LigandBDBM50213559(2-(N-(2-Ffuorophenyl)pyrrol-3-yl) acetic acid | CH...)Copy SMILESCopy InChI

Affinity DataIC50:  3.40E+4nMAssay Description:Inhibition of rat liver 3-alpha-HSD assessed as 5-beta-dihydrocortisone reductionMore data for this Ligand-Target Pair

Target InfoReactome pathwayKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI