Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetAcyl-CoA desaturase 1(Rattus norvegicus (Rat))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL

LigandBDBM50364014(CHEMBL1950402)Copy SMILESCopy InChI

Affinity DataIC50:  20nMAssay Description:Inhibition of rat SCD1More data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidPatents

In DepthDetails ArticlePubMed
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TargetAcyl-CoA desaturase 1(Rattus norvegicus (Rat))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL

LigandBDBM50364014(CHEMBL1950402)Copy SMILESCopy InChI

Affinity DataIC50:  75nMAssay Description:Inhibition of SCD1 in Sprague-Dawley rat hepatocytes assessed as conversion of [14C]oleic acid formation by HPLC analysisMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidPatents

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetStearoyl-CoA desaturase(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL

LigandBDBM50364014(CHEMBL1950402)Copy SMILESCopy InChI

Affinity DataIC50:  780nMAssay Description:Inhibition of human SCD1 expressed in human HepG2 cells assessed as conversion of [14C]stearic acid to [14C]oleic acidMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidPatents

In DepthDetails ArticlePubMed
Copy BDB DOI