Home
About
Info
Download
WebServices
Contact
Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
4
hits in this display
Target
Kelch-like ECH-associated protein 1
(Homo sapiens (Human))
University Of Copenhagen
Curated by
ChEMBL
Ligand
BDBM36500
(2-(5-Chlorobenzo[b]thiophen-3-yl)acetic acid, 1 | ...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 3.40E+6nM
Assay Description:
Inhibition of recombinant human His-tagged Keap1 kelch domain (321 to 609 residues) expressed in Escherichia coli BL21(DE3) cells to Cy5-Nrf2 (unknow...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
MMDB
PC cid
PC sid
PDB
Patents
In Depth
Details
PubMed
Copy BDB DOI
Target
Farnesyl pyrophosphate synthase
(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Ligand
BDBM36500
(2-(5-Chlorobenzo[b]thiophen-3-yl)acetic acid, 1 | ...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >5.00E+5nM
pH: 7.4 T: 2°C
Assay Description:
A biophysical assay using NMR spectroscopy to identify fragments with higher binding affinity to human recombinant FPPS.
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
MMDB
PC cid
PC sid
PDB
Patents
In Depth
Details
Article
PubMed
MMDB
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Farnesyl pyrophosphate synthase
(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Ligand
BDBM36500
(2-(5-Chlorobenzo[b]thiophen-3-yl)acetic acid, 1 | ...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >5.00E+8nM
Assay Description:
Inhibition of FPPS (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
MMDB
PC cid
PC sid
PDB
Patents
In Depth
Details
Article
PubMed
MMDB
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Kelch-like ECH-associated protein 1
(Homo sapiens (Human))
University Of Copenhagen
Curated by
ChEMBL
Ligand
BDBM36500
(2-(5-Chlorobenzo[b]thiophen-3-yl)acetic acid, 1 | ...)
Copy SMILES
Copy InChI
Affinity Data
Kd: 8.40E+5nM
Assay Description:
Binding affinity to Keap1 kelch domain (unknown origin) by surface plasmon resonance assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
MMDB
PC cid
PC sid
PDB
Patents
In Depth
Details
PubMed
Copy BDB DOI