Compile Data Set for Download or QSAR
maximum 50k data

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetAcyl-CoA desaturase 1(Rattus norvegicus (Rat))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50356907(CHEMBL1915556)
Affinity DataIC50:  49nMAssay Description:Inhibition of rat SCD by rat microsomal assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA desaturase 1(Rattus norvegicus (Rat))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50356907(CHEMBL1915556)
Affinity DataIC50:  975nMAssay Description:Inhibition of SCD in rat hepatocytes assessed as conversion of [14C]-stearic acid to [14C]-oleic acid preincubated for 15 mins measured after 1 hrs b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStearoyl-CoA desaturase(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50356907(CHEMBL1915556)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of SCD in human HepG2 cells assessed as conversion of [1-(14)C]-stearic acid to (14)C-oleic acidMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed