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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
9
hits in this display
Target
Dual specificity mitogen-activated protein kinase kinase 4
(Homo sapiens (Human))
Northwestern University
US Patent
Ligand
BDBM558848
(US11370770, Compound 6a)
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Affinity Data
IC50: 180nM
Assay Description:
Kinase activity of recombinant active full-length human MEK4 (Carna Biosciences) was measured using the ADP-Glo assay (Promega) with 3 μM recomb...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Dual specificity mitogen-activated protein kinase kinase 4
(Homo sapiens (Human))
Northwestern University
US Patent
Ligand
BDBM558848
(US11370770, Compound 6a)
Copy SMILES
Copy InChI
Affinity Data
IC50: 460nM
Assay Description:
Kinase activity of recombinant active full-length human MEK4 (Carna Biosciences) was measured using the ADP-Glo assay (Promega) with 3 μM recomb...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Dual specificity mitogen-activated protein kinase kinase 4
(Homo sapiens (Human))
Northwestern University
US Patent
Ligand
BDBM558848
(US11370770, Compound 6a)
Copy SMILES
Copy InChI
Affinity Data
IC50: 640nM
Assay Description:
Kinase activity of recombinant active full-length human MEK4 (Carna Biosciences) was measured using the ADP-Glo assay (Promega) with 3 μM recomb...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Mitogen-activated protein kinase 1
(Homo sapiens (Human))
Northwestern University
US Patent
Ligand
BDBM558848
(US11370770, Compound 6a)
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Copy InChI
Affinity Data
IC50: 7.20E+3nM
Assay Description:
Kinase activity of recombinant active full-length human MEK4 (Carna Biosciences) was measured using the ADP-Glo assay (Promega) with 3 μM recomb...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Mitogen-activated protein kinase 7
(Homo sapiens (Human))
Northwestern University
US Patent
Ligand
BDBM558848
(US11370770, Compound 6a)
Copy SMILES
Copy InChI
Affinity Data
IC50: 8.30E+3nM
Assay Description:
Kinase activity of recombinant active full-length human MEK4 (Carna Biosciences) was measured using the ADP-Glo assay (Promega) with 3 μM recomb...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Mitogen-activated protein kinase 6
(Homo sapiens (Human))
Northwestern University
US Patent
Ligand
BDBM558848
(US11370770, Compound 6a)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.00E+4nM
Assay Description:
Kinase activity of recombinant active full-length human MEK4 (Carna Biosciences) was measured using the ADP-Glo assay (Promega) with 3 μM recomb...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
MAP kinase-activated protein kinase 3
(Homo sapiens (Human))
Northwestern University
US Patent
Ligand
BDBM558848
(US11370770, Compound 6a)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.60E+4nM
Assay Description:
Kinase activity of recombinant active full-length human MEK4 (Carna Biosciences) was measured using the ADP-Glo assay (Promega) with 3 μM recomb...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
MAP kinase-activated protein kinase 5
(Homo sapiens (Human))
Northwestern University
US Patent
Ligand
BDBM558848
(US11370770, Compound 6a)
Copy SMILES
Copy InChI
Affinity Data
IC50: >2.70E+4nM
Assay Description:
Kinase activity of recombinant active full-length human MEK4 (Carna Biosciences) was measured using the ADP-Glo assay (Promega) with 3 μM recomb...
More data for this Ligand-Target Pair
Target Info
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
MAP kinase-activated protein kinase 2
(Homo sapiens (Human))
Northwestern University
US Patent
Ligand
BDBM558848
(US11370770, Compound 6a)
Copy SMILES
Copy InChI
Affinity Data
IC50: >2.70E+4nM
Assay Description:
Kinase activity of recombinant active full-length human MEK4 (Carna Biosciences) was measured using the ADP-Glo assay (Promega) with 3 μM recomb...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI